Rojas-Carrera Sonia Irma, Márquez-Celedonio Félix Guillermo, Lagunes-Mijangos Adrián, González-Arriola Víctor Manuel
Unidad de Medicina Familiar 61, Instituto Mexicano del Seguro Social, Veracruz, Veracruz, México.
Rev Med Inst Mex Seguro Soc. 2013 May-Jun;51(3):336-9.
to assess the specificity and sensibility of the O'Sullivan test for gestational diabetes in early pregnancy.
a pilot study in 50 women with low-risk of pregnancy, without history of alteration of glucose was done. The O'Sullivan test consisted in the administration of 50 g of glucose; glycemia was measured 60 minutes after, between weeks 14 and 23 and between weeks 24 and 28 of pregnancy. Value was considered positive with a glycemia = 140 mg/dL. We calculated sensitivity, specificity and predictive values.
O'Sullivan test performed between weeks 14 and 23 was positive in three pregnant women (6 %), and between weeks 24 and 28, in four (8 %); there was no statistical difference in both measurements (p > 0.05). The sensitivity was 75 % (95 %, CI 30.1 % to 95.4 %), and the specificity 100.0 % (95 %, CI 92.3 % to 100 %).
the O'Sullivan test performed between weeks 14 and 23 of gestation showed good sensitivity and specificity in the diagnosis of early gestational pregnancy.
评估奥沙利文试验在孕早期对妊娠期糖尿病的特异性和敏感性。
对50名妊娠风险低且无血糖异常史的女性进行了一项初步研究。奥沙利文试验包括给予50克葡萄糖；在妊娠第14至23周以及第24至28周期间，给药60分钟后测量血糖。血糖值≥140毫克/分升被视为阳性。我们计算了敏感性、特异性和预测值。
在第14至23周进行的奥沙利文试验中，三名孕妇（6%）呈阳性，在第24至28周期间，四名孕妇（8%）呈阳性；两次测量之间无统计学差异（p>0.05）。敏感性为75%（95%，可信区间30.1%至95.4%），特异性为100.0%（95%，可信区间92.3%至100%）。
在妊娠第14至23周进行的奥沙利文试验在早期妊娠诊断中显示出良好的敏感性和特异性。
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