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犬猫非甾体抗炎药之外的门诊口服镇痛药:循证方法

Outpatient oral analgesics in dogs and cats beyond nonsteroidal antiinflammatory drugs: an evidence-based approach.

作者信息

KuKanich Butch

机构信息

Department of Anatomy and Physiology, Kansas State University, Manhattan, KS 66506, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):1109-25. doi: 10.1016/j.cvsm.2013.04.007. Epub 2013 May 29.

Abstract

This article evaluates the current literature on oral analgesics and analgesic adjuncts in dogs and cats. An overview of how dosing recommendations are made covering controlled clinical trials, experimental study design, and pharmacokinetic studies is included. The weight of evidence for each drug is reviewed and compared with the gold standard, controlled clinical trials. Other evidence such as experimental studies, extrapolation of pharmacokinetic studies, and case reports/series is also considered. It important to know from what data dosing recommendations are derived and how much evidence supports the use of oral analgesics and analgesic adjuncts in dogs and cats.

摘要

本文评估了目前关于犬猫口服镇痛药及镇痛辅助药物的文献。文中涵盖了关于如何制定给药建议的概述,包括对照临床试验、实验研究设计和药代动力学研究。对每种药物的证据权重进行了审查,并与金标准——对照临床试验进行了比较。还考虑了其他证据,如实验研究、药代动力学研究的外推以及病例报告/系列。了解给药建议是基于哪些数据得出的,以及有多少证据支持在犬猫中使用口服镇痛药和镇痛辅助药物非常重要。

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