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老年人抑郁症患者戒酒和危险饮酒的相关因素:NESDO 研究。

Correlates of alcohol abstinence and at-risk alcohol consumption in older adults with depression: the NESDO study.

机构信息

Parnassia Psychiatric Institute, The Hague, The Netherlands.

Parnassia Psychiatric Institute, The Hague, The Netherlands.

出版信息

Am J Geriatr Psychiatry. 2014 Sep;22(9):866-74. doi: 10.1016/j.jagp.2013.04.006. Epub 2013 Jul 23.

Abstract

OBJECTIVES

To compare alcohol use between depressed and nondepressed older adults, and to investigate correlates of alcohol abstinence and at-risk alcohol consumption in depressed older adults.

DESIGN

Cross-sectional study.

SETTING

Netherlands Study of Depression in Older Persons (NESDO).

PARTICIPANTS

A total of 373 participants (mean [standard deviation] age: 70.6 [7.3] years; 66% women) diagnosed with a depressive disorder, and 128 nondepressed participants.

MEASUREMENTS

Alcohol use was assessed with the Alcohol Use Disorders Identification Test (AUDIT). Participants were categorized into abstainers (AUDIT score: 0), moderate drinkers (AUDIT score: 1-4), and at-risk drinkers (AUDIT score: ≥5). Multinomial logistic regression analysis was performed with AUDIT categories as outcome, and demographic, social, somatic, and psychological variables as determinants.

RESULTS

The depressed group consisted of 40.2% abstainers, 40.8% moderate drinkers, and 19.0% at-risk drinkers. The depressed participants were more often abstinent and less often moderate drinkers than the nondepressed participants; they did not differ in at-risk drinking. Depressed abstainers more often used benzodiazepines but less often used antidepressants, and they had a poorer cognitive function than depressed moderate drinkers. Depressed at-risk drinkers were more often smokers and had fewer functional limitations but more severe depressive symptoms than depressed moderate drinkers.

CONCLUSIONS

Although alcohol abstinence was more common in depressed than in nondepressed older adults, 19% of depressed persons were at-risk drinkers. Because at-risk drinking is associated with more severe depression and may have a negative impact on health and treatment outcome, it is important that physicians consider alcohol use in depressed older adults.

摘要

目的

比较抑郁和非抑郁老年人群体的饮酒情况,并探究抑郁老年人群体中戒酒和危险饮酒的相关因素。

设计

横断面研究。

地点

荷兰老年人抑郁研究(NESDO)。

参与者

共 373 名被诊断为抑郁障碍的参与者(平均[标准差]年龄:70.6[7.3]岁;66%为女性)和 128 名非抑郁参与者。

测量方法

使用酒精使用障碍识别测试(AUDIT)评估饮酒情况。参与者分为戒酒者(AUDIT 评分:0)、适度饮酒者(AUDIT 评分:1-4)和危险饮酒者(AUDIT 评分:≥5)。使用 AUDIT 类别作为因变量,人口统计学、社会、躯体和心理变量作为决定因素,进行多项逻辑回归分析。

结果

抑郁组包括 40.2%的戒酒者、40.8%的适度饮酒者和 19.0%的危险饮酒者。与非抑郁组相比,抑郁组参与者更常戒酒,更少为适度饮酒者;但两组在危险饮酒方面没有差异。抑郁戒酒者更常使用苯二氮䓬类药物,但较少使用抗抑郁药,且认知功能较抑郁适度饮酒者差。抑郁危险饮酒者更常吸烟,且功能障碍较少,但抑郁症状更严重。

结论

尽管抑郁老年人群体中戒酒更为常见,但仍有 19%的抑郁者为危险饮酒者。由于危险饮酒与更严重的抑郁相关,并且可能对健康和治疗结果产生负面影响,因此医生应考虑抑郁老年人群体中的饮酒情况。

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