1,2-O-异亚丙基-α-l-呋喃果糖、1,2:4,6-二-O-异亚丙基-α-L-呋喃果糖及其衍生物的合成与光谱数据修订的再研究。

A reinvestigation of the synthesis and revision of spectral data of 1,2-O-isopropylidene-α-l-sorbofuranose, 1,2:4,6-di-O-isopropylidene-α-L-sorbofuranose and derivatives.

机构信息

Institut de Chimie Organique et Analytique (ICOA), UMR 7311, Université d'Orléans and CNRS, Rue de Chartres, BP 6759, 45067 Orléans cedex 2, France.

出版信息

Carbohydr Res. 2013 Oct 18;380:23-8. doi: 10.1016/j.carres.2013.05.019. Epub 2013 Jun 11.

DOI:10.1016/j.carres.2013.05.019

PMID:23896160

Abstract

Mono- and di-O-isopropylidene-l-sorbofuranose derivatives are important starting materials for the synthesis of modified sugars and useful chiral compounds. However, several inconsistencies in the spectral data of these compounds and erroneous structural assignments have been noted in the literature. The unambiguous synthesis of 1,2:4,6-di-O-isopropylidene-α-L-sorbofuranose and derivatives of 1,2- and 2,3-O-isopropylidene-α-L-sorbofuranoses has been achieved and definitive spectral data on these compounds are provided.

摘要

单-和二-O-异亚丙基-L-山梨呋喃糖衍生物是合成修饰糖和有用手性化合物的重要起始材料。然而，这些化合物的光谱数据存在一些不一致之处，并且在文献中也指出了错误的结构分配。已经实现了 1,2:4,6-二-O-异亚丙基-α-L-山梨呋喃糖和 1,2-和 2,3-O-异亚丙基-α-L-山梨呋喃糖衍生物的明确合成，并提供了这些化合物的明确光谱数据。