Miyahara Shunsuke, Okita Yutaka
Division of Cardiovascular Surgery, Kobe University School of Medicine, Kobe, Japan.
Kyobu Geka. 2013 Jul;66(8 Suppl):649-54.
Our experiences of secondary aortic root replacement after proximal aortic operation and their technical details are presented. Between November 1999 and February 2013, 50 patients underwent reoperative aortic root replacement(34 male, mean age 59.6±13.1 years). The mode of previous operation was ascending and arch replacement in 21, aortic valve replacement (AVR) in 19, and aortic root replacement in 10. Indications for reoperation included root dilation( n=13), aortic root abscess( n=13), residual proximal dissection (n=12), formation of pseudoaneurysm (n=5)and graft infection (n=3), and non-structural valve dysfunction (n=4). Mean interval from 1st operation was 84.3±85.2 months (range, 0.8 month~11.8 years). At reoperation, 29(58.0%)patients had Bentall operation, 11(22.0%)had valve sparing root replacement, 5(10.0%)had prosthetic valve preserved root replacement and 5(10.0%)had partial replacement of Valsalva sinus without reimplantation of coronaries. In-hospital mortality was 8.0%(4 of 50). The cause of mortality was sepsis in 2, low-output syndrome in 1 and hemorrhagic stroke in 1. During follow-up, 2 patients had a 3rd-time root replacement for pseudoaneurysm formation and infective endocarditis. Other 2 patients needed coronary artery bypass grafting(CABG) and AVR for structural valve deterioration. Freedom from 3rd-time aortic root related operation was 90.2±4.7% at 10 years. Actuarial survival after reoperation was 84.6±6.3% at 10 years. In conclusion, reoperative aortic root replacement can be performed with acceptable outcomes even in patients with complicated aortic pathologies.
本文介绍了我们在近端主动脉手术后进行二次主动脉根部置换的经验及其技术细节。1999年11月至2013年2月期间,50例患者接受了再次主动脉根部置换手术(男性34例,平均年龄59.6±13.1岁)。既往手术方式为升主动脉和主动脉弓置换21例,主动脉瓣置换(AVR)19例,主动脉根部置换10例。再次手术的指征包括根部扩张(n=13)、主动脉根部脓肿(n=13)、残余近端夹层(n=12)、假性动脉瘤形成(n=5)和移植物感染(n=3),以及非结构性瓣膜功能障碍(n=4)。首次手术至再次手术的平均间隔时间为84.3±85.2个月(范围为0.8个月至11.8年)。再次手术时,29例(58.0%)患者接受了Bentall手术,11例(22.0%)接受了保留瓣膜的根部置换,5例(10.0%)接受了保留人工瓣膜的根部置换,5例(10.0%)接受了Valsalva窦部分置换且未再植入冠状动脉。住院死亡率为8.0%(50例中有4例)。死亡原因分别为败血症2例、低心排综合征1例和出血性卒中1例。随访期间,2例患者因假性动脉瘤形成和感染性心内膜炎接受了第三次根部置换。另外2例患者因结构性瓣膜退变需要冠状动脉旁路移植术(CABG)和AVR。10年时无需进行第三次主动脉根部相关手术的自由度为90.2±4.7%。再次手术后10年的精算生存率为84.6±6.3%。总之,即使是患有复杂主动脉病变的患者,再次主动脉根部置换手术也能取得可接受的结果。