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卡绍维茨定律的观察——晚期先天性梅毒:以腭穿孔和鞍鼻畸形为表现特征。

Observance of Kassowitz law-late congenital syphilis: Palatal perforation and saddle nose deformity as presenting features.

作者信息

Balaji Govindan, Kalaivani Subramanian

机构信息

Department of Sexually Transmitted Disease, Govt Mohan Kumaramangalam Medial College Hospital, Salem, Tamilnadu, India.

出版信息

Indian J Sex Transm Dis AIDS. 2013 Jan;34(1):35-7. doi: 10.4103/0253-7184.112869.

Abstract

Late congenital syphilis refers to the people with syphilis from the age of 2 to 30 years. We report a case of late congenital syphilis in a 9 year old girl with perforation of palate and saddle nose deformity. Kassowitz law was also observed (if a woman with untreated syphilis has series of pregnancies, the likelihood of infection of the fetus in later pregnancies becomes less). Venereal Disease Research Laboratory (VDRL) and Treponema pallidum hemagglutination (TPHA) were reactive. Computed tomography (CT) scan of paranasal sinus showed maxillary and nasal polyps. The case reported here is a rare presentation of late congenital syphilis with perforation of palate and saddle nose deformity.

摘要

晚期先天性梅毒是指2至30岁患有梅毒的人群。我们报告一例9岁女童晚期先天性梅毒病例,该女童存在腭穿孔和鞍鼻畸形。同时也观察到了卡索维茨定律(如果患有未经治疗梅毒的女性多次怀孕,那么在后续妊娠中胎儿被感染的可能性会降低)。性病研究实验室(VDRL)和梅毒螺旋体血细胞凝集试验(TPHA)呈阳性反应。鼻窦计算机断层扫描(CT)显示上颌窦和鼻腔息肉。此处报告的病例是晚期先天性梅毒伴有腭穿孔和鞍鼻畸形的罕见表现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d383/3730472/f992cf90c681/IJSTD-34-35-g001.jpg

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