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来自露珠杜鹃的新天然化合物。

New natural compounds from Rhododendron lepidotum.

机构信息

a Natural Product Chemistry Division, Indian Institute of Integrative Medicine (CSIR) , Srinagar , 190 005 , India.

出版信息

Nat Prod Res. 2013;27(21):2033-8. doi: 10.1080/14786419.2013.824439. Epub 2013 Aug 13.

Abstract

Phytochemical investigation of the aerial parts of Rhododendron lepidotum yielded 8-[2',6'-dimethoxy-4'-(1″,2″,3″-trihydroxy-propyl)-phenyl]-7-hydroxy benzopyranone (1), 3-O-β-d-glycopyranosyl betulinic amide (2) and 8-hydroxy-7,7'-oxydicoumarin (4) and five known compounds. Among the known molecules, betulinic amide (3) was earlier reported as a semi-synthetic product. The structures of new molecules 1, 2 and 4 were elucidated on the basis of extensive spectroscopic investigations (1D NMR, 2D NMR and mass spectrometry).

摘要

对密枝杜鹃(Rhododendron lepidotum)的地上部分进行的植物化学研究得到了 8-[2',6'-二甲氧基-4'-(1″,2″,3″-三羟基丙基)-苯基]-7-羟基苯并吡喃酮(1)、3-O-β-d-吡喃葡萄糖基白桦脂酰胺(2)和 8-羟基-7,7'-氧化二苯并吡喃酮(4)以及 5 种已知化合物。在已知分子中,白桦脂酰胺(3)以前被报道为半合成产物。新分子 1、2 和 4 的结构是根据广泛的光谱研究(1D NMR、2D NMR 和质谱)阐明的。

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