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验证洛杉矶院外脑卒中筛查(LAPSS)在中国城市急救医疗服务人群中的应用。

Validation of the Los Angeles pre-hospital stroke screen (LAPSS) in a Chinese urban emergency medical service population.

机构信息

Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

出版信息

PLoS One. 2013 Aug 7;8(8):e70742. doi: 10.1371/journal.pone.0070742. eCollection 2013.

Abstract

BACKGROUND AND PURPOSE

Early and accurate diagnosis of stroke by emergency medical service (EMS) paramedics is critical for reducing pre-hospital delays. The Los Angeles pre-hospital stroke screen (LAPSS) has been widely used as a validated screening tool for early identifying stroke patients by EMS paramedics. However, validation of LAPSS has never been performed in Chinese stroke population. This study is aimed to verify the LAPSS for early identifying stroke patients in a Chinese urban EMS.

METHODS

76 paramedics of five urban first aid stations attached to Beijing 120 EMS were involved. The paramedics were trained by professionals to quickly screen patients based on LAPSS. Potential "target stroke" individuals who met the base LAPSS screen criteria were identified. Sensitivity and specificity analyses of the LAPSS were calculated.

RESULTS

From June 10, 2009 to June 10, 2010, paramedics transported a total of 50,220 patients. 1550 patients who met the baseline screen criteria were identified as the potential "target stroke" population. 1130 patients had the completed LAPSS information datasheet and 997 patients were clinically diagnosed with stroke. The average time of completing the LAPSS was 4.3±3.0 minutes (median, 5 minutes). The sensitivity and specificity of the LAPSS in this study was 78.44% and 90.22%, respectively. After adjusting for age factor by excluding patients of >45 years old, the sensitivity was significantly increased to 82.95% with specificity unchanged.

CONCLUSION

The paramedics of Beijing 120 EMS could efficiently use LAPSS as a screening tool for early identifying stroke patients. While the sensitivity of LAPSS in Chinese urban patient population was lower than those reported in previous LAPSS validation studies, the specificity was consistent with these studies. After excluded the item of "Age>45 years", the sensitivity was improved.

摘要

背景与目的

通过急救医疗服务(EMS)护理人员对中风进行早期、准确的诊断,对于减少院前延误至关重要。洛杉矶院前中风筛查(LAPSS)已被广泛用作 EMS 护理人员早期识别中风患者的有效筛查工具。然而,LAPSS 在中国中风人群中的验证从未进行过。本研究旨在验证 LAPSS 在中国城市 EMS 中早期识别中风患者的能力。

方法

本研究共纳入了来自北京 120 EMS 的 5 个城市急救站的 76 名护理人员。这些护理人员接受了专业人员的培训,以根据 LAPSS 快速筛查患者。符合基础 LAPSS 筛查标准的潜在“目标中风”个体被识别出来。计算了 LAPSS 的敏感性和特异性分析。

结果

从 2009 年 6 月 10 日至 2010 年 6 月 10 日,护理人员共转运了 50220 名患者。确定了 1550 名符合基线筛查标准的患者为潜在“目标中风”人群。1130 名患者完成了 LAPSS 信息数据表,997 名患者被临床诊断为中风。完成 LAPSS 的平均时间为 4.3±3.0 分钟(中位数为 5 分钟)。本研究中 LAPSS 的敏感性和特异性分别为 78.44%和 90.22%。排除>45 岁的患者后,根据年龄因素进行调整,敏感性显著提高至 82.95%,特异性不变。

结论

北京 120 EMS 的护理人员可以有效地使用 LAPSS 作为早期识别中风患者的筛查工具。虽然 LAPSS 在中国城市患者人群中的敏感性低于之前的 LAPSS 验证研究报告,但特异性与这些研究一致。排除“年龄>45 岁”项目后,敏感性得到提高。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adc0/3737357/bee04dd69696/pone.0070742.g001.jpg

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