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一般美国人群中伴有或不伴有良性前列腺增生的勃起功能障碍:美国国家健康和健康调查分析。

Erectile dysfunction with or without coexisting benign prostatic hyperplasia in the general US population: analysis of US National Health and Wellness Survey.

机构信息

Eli Lilly and Company , Indianapolis, IN , USA.

出版信息

Curr Med Res Opin. 2013 Dec;29(12):1709-17. doi: 10.1185/03007995.2013.837385. Epub 2013 Sep 23.

Abstract

OBJECTIVE

Erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) commonly affect older men. There is limited epidemiology information on coexisting ED and BPH. This study assessed self-reported prevalence of ED with or without a diagnosis of BPH (ED/DxBPH versus ED only) in US men.

METHODS

Men ≥40 years old, who reported experiencing ED in the past 6 months with or without a diagnosis of BPH, were identified from the nationally representative 2011 US National Health and Wellness Survey (NHWS) - a cross-sectional, self-administered online survey. Unpaired t-tests were used to compare characteristics between ED-only and ED/DxBPH populations.

RESULTS

The prevalence of ED only and ED/DxBPH was 24.6% and 4.9% (mean ages of 60 and 68 years, respectively). About two-thirds of those with ED only and ED/DxBPH reported speaking to their physician about ED. About 23% of either group reported currently using ED medication and 11.7% of men with ED only were prescribed ED medication by a urologist, compared to 31.1% with ED/DxBPH. Approximately 51.7% of men with ED/DxBPH were taking BPH medication. Overall, 37.3% of men with ED only and 74.6% with ED/DxBPH reported moderate-to-severe urinary symptoms on the American Urological Association-Symptom Index (AUA-SI ≥8).

CONCLUSION

While self-reported ED is common, few men with ED in the US population report being diagnosed with BPH. The majority of ED only and ED/DxBPH men reported speaking to a physician about ED; however, few reported currently taking ED medication. A majority of men with ED/DxBPH reported an AUA-SI score ≥8, but only half reported taking BPH medications. Thus, although men are experiencing erectile or urinary symptoms, many remain untreated. A limitation of this study is that symptoms and diagnosis were self-reported and may not reflect how these conditions are diagnosed in a healthcare setting; however, patient self-report provides a unique perspective on the burden associated with these conditions.

摘要

目的

勃起功能障碍(ED)和良性前列腺增生(BPH)常影响老年男性。有关同时患有 ED 和 BPH 的流行病学信息有限。本研究评估了美国男性中报告的 ED 患病率,包括有或无 BPH 诊断的 ED(ED/DxBPH 与 ED 仅)。

方法

从具有代表性的 2011 年美国国家健康和健康调查(NHWS)中确定了过去 6 个月内报告患有 ED 且有或无 BPH 诊断的年龄≥40 岁的男性。使用未配对的 t 检验比较 ED 仅和 ED/DxBPH 人群的特征。

结果

ED 仅和 ED/DxBPH 的患病率分别为 24.6%和 4.9%(平均年龄分别为 60 和 68 岁)。约三分之二的 ED 仅和 ED/DxBPH 患者与医生讨论过 ED。约 23%的患者报告目前正在使用 ED 药物,11.7%的 ED 仅患者被泌尿科医生开了 ED 药物,而 ED/DxBPH 患者为 31.1%。大约 51.7%的 ED/DxBPH 患者正在服用 BPH 药物。总体而言,37.3%的 ED/DxBPH 患者的美国泌尿协会症状指数(AUA-SI≥8)报告中度至重度的尿症状,而 ED 仅患者为 74.6%。

结论

虽然自我报告的 ED 很常见,但美国人群中很少有 ED 患者被诊断为 BPH。大多数 ED 仅和 ED/DxBPH 男性报告与医生讨论过 ED;然而,很少有人报告目前正在服用 ED 药物。大多数 ED/DxBPH 患者的 AUA-SI 评分≥8,但只有一半的患者报告服用 BPH 药物。因此,尽管男性正在经历勃起或尿症状,但许多人仍未得到治疗。本研究的一个局限性是症状和诊断是自我报告的,可能无法反映这些疾病在医疗保健环境中的诊断情况;然而,患者的自我报告提供了对这些疾病相关负担的独特视角。

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