Eli Lilly and Company , Indianapolis, IN , USA.
Curr Med Res Opin. 2013 Dec;29(12):1709-17. doi: 10.1185/03007995.2013.837385. Epub 2013 Sep 23.
Erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) commonly affect older men. There is limited epidemiology information on coexisting ED and BPH. This study assessed self-reported prevalence of ED with or without a diagnosis of BPH (ED/DxBPH versus ED only) in US men.
Men ≥40 years old, who reported experiencing ED in the past 6 months with or without a diagnosis of BPH, were identified from the nationally representative 2011 US National Health and Wellness Survey (NHWS) - a cross-sectional, self-administered online survey. Unpaired t-tests were used to compare characteristics between ED-only and ED/DxBPH populations.
The prevalence of ED only and ED/DxBPH was 24.6% and 4.9% (mean ages of 60 and 68 years, respectively). About two-thirds of those with ED only and ED/DxBPH reported speaking to their physician about ED. About 23% of either group reported currently using ED medication and 11.7% of men with ED only were prescribed ED medication by a urologist, compared to 31.1% with ED/DxBPH. Approximately 51.7% of men with ED/DxBPH were taking BPH medication. Overall, 37.3% of men with ED only and 74.6% with ED/DxBPH reported moderate-to-severe urinary symptoms on the American Urological Association-Symptom Index (AUA-SI ≥8).
While self-reported ED is common, few men with ED in the US population report being diagnosed with BPH. The majority of ED only and ED/DxBPH men reported speaking to a physician about ED; however, few reported currently taking ED medication. A majority of men with ED/DxBPH reported an AUA-SI score ≥8, but only half reported taking BPH medications. Thus, although men are experiencing erectile or urinary symptoms, many remain untreated. A limitation of this study is that symptoms and diagnosis were self-reported and may not reflect how these conditions are diagnosed in a healthcare setting; however, patient self-report provides a unique perspective on the burden associated with these conditions.
勃起功能障碍(ED)和良性前列腺增生(BPH)常影响老年男性。有关同时患有 ED 和 BPH 的流行病学信息有限。本研究评估了美国男性中报告的 ED 患病率,包括有或无 BPH 诊断的 ED(ED/DxBPH 与 ED 仅)。
从具有代表性的 2011 年美国国家健康和健康调查(NHWS)中确定了过去 6 个月内报告患有 ED 且有或无 BPH 诊断的年龄≥40 岁的男性。使用未配对的 t 检验比较 ED 仅和 ED/DxBPH 人群的特征。
ED 仅和 ED/DxBPH 的患病率分别为 24.6%和 4.9%(平均年龄分别为 60 和 68 岁)。约三分之二的 ED 仅和 ED/DxBPH 患者与医生讨论过 ED。约 23%的患者报告目前正在使用 ED 药物,11.7%的 ED 仅患者被泌尿科医生开了 ED 药物,而 ED/DxBPH 患者为 31.1%。大约 51.7%的 ED/DxBPH 患者正在服用 BPH 药物。总体而言,37.3%的 ED/DxBPH 患者的美国泌尿协会症状指数(AUA-SI≥8)报告中度至重度的尿症状,而 ED 仅患者为 74.6%。
虽然自我报告的 ED 很常见,但美国人群中很少有 ED 患者被诊断为 BPH。大多数 ED 仅和 ED/DxBPH 男性报告与医生讨论过 ED;然而,很少有人报告目前正在服用 ED 药物。大多数 ED/DxBPH 患者的 AUA-SI 评分≥8,但只有一半的患者报告服用 BPH 药物。因此,尽管男性正在经历勃起或尿症状,但许多人仍未得到治疗。本研究的一个局限性是症状和诊断是自我报告的,可能无法反映这些疾病在医疗保健环境中的诊断情况;然而,患者的自我报告提供了对这些疾病相关负担的独特视角。