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含咪唑、吲哚和吡咯基团的三甲氧基苯和三甲苯基化合物作为识别单元:对碳水化合物结合性质的评价。

Trimethoxybenzene- and trimethylbenzene-based compounds bearing imidazole, indole and pyrrole groups as recognition units: synthesis and evaluation of the binding properties towards carbohydrates.

机构信息

Institut für Organische Chemie, Technische Universität Bergakademie Freiberg, Leipziger Strasse 29, 09596 Freiberg, Germany.

出版信息

Org Biomol Chem. 2013 Oct 14;11(38):6569-79. doi: 10.1039/c3ob41540f. Epub 2013 Aug 28.

Abstract

The aim of the study was to evaluate the potential of trimethoxybenzene- and trimethylbenzene-based compounds bearing imidazole or indole groups as recognition sites in the complexation of carbohydrates. Representatives of these compounds were prepared and their binding properties toward selected carbohydrates evaluated. The results of the binding studies were compared with those obtained for the prepared pyrrole bearing analogues and for the previously described triethylbenzene-based receptors.

摘要

本研究旨在评估带有咪唑或吲哚基团的三甲氧基苯和三甲苯基化合物作为识别位点,用于碳水化合物的络合。这些化合物的代表物被制备出来,并对其与选定碳水化合物的结合性质进行了评估。将结合研究的结果与已制备的吡咯类似物和以前描述的三乙基苯基受体的结果进行了比较。

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