Federal Psychiatric Hospital, Ugbowo Lagos Road, Benin City, 30001, Nigeria.
Ther Adv Psychopharmacol. 2012 Oct;2(5):169-77. doi: 10.1177/2045125312453158.
Antipsychotic long-acting injections (LAIs) reduce covert nonadherence with medication in the clinical management of psychotic disorders. However, they are variably utilised by clinicians, especially in the long term. Factors including poor knowledge, stigma and perceived coercion can all adversely influence LAI utilisation. Previous research has emanated almost exclusively from developed countries. This study explores the knowledge and attitudes of psychiatrists and trainees in Nigeria towards LAIs.
A cross-sectional study was undertaken among mental health professionals in Nigeria using a pre-existing questionnaire.
Participant psychiatrists (n = 128) expressed positive attitudes towards LAIs. Their knowledge concerning LAIs and its side effects was fair. The participants reported that nearly half (41.7%) of their patients with a psychotic illness were on LAIs. Those who reported a high prescribing rate for LAIs (>40%) were more likely to endorse more positive 'patient-centred attitudes' (p < 0.04). In contrast to previous reports, psychiatrists reported that patients were less likely to feel ashamed when on LAIs, though most endorsed the statement that force was required during LAI administration.
The desirability of treatment by injections differs in Africa in comparison to Western cultures, possibly due to the increased potency that injections are perceived to have. This is perhaps evidenced by high rates reported for use of LAIs. Nigerian psychiatrists had positive attitudes to LAIs but their knowledge, particularly regarding side effects, was fair and needs to be improved. Providing information to patients prior to antipsychotic treatment may enhance informed consent in a country where medical paternalism is still relatively strong.
抗精神病长效注射剂(LAIs)可减少精神障碍临床治疗中药物的隐性不依从。然而,临床医生对其使用情况各不相同,尤其是在长期治疗中。包括知识不足、污名化和被感知的强制等因素都会对 LAI 的使用产生不利影响。之前的研究几乎全部来自发达国家。本研究旨在探索尼日利亚精神科医生和受训者对 LAI 的知识和态度。
在尼日利亚,使用预先存在的问卷对精神卫生专业人员进行了横断面研究。
参与研究的精神科医生(n=128)对 LAI 持积极态度。他们对 LAI 及其副作用的了解尚可。报告称,近一半(41.7%)患有精神病的患者正在接受 LAI 治疗。报告 LAIs 使用率较高(>40%)的参与者更有可能认可更积极的“以患者为中心的态度”(p<0.04)。与之前的报告不同,医生报告称,患者在接受 LAI 治疗时不太可能感到羞耻,尽管大多数人认为在 LAI 给药时需要强制。
与西方文化相比,非洲对注射治疗的期望不同,这可能是由于人们认为注射具有更高的效力。这或许可以从报告的高 LAI 使用率中得到证明。尼日利亚精神科医生对 LAI 持积极态度,但他们的知识,特别是关于副作用的知识,尚可但需要提高。在医疗家长主义仍然相对较强的国家,在开始抗精神病治疗之前向患者提供信息可能会增强知情同意。