肺部非典型性组织细胞增生症。
Atypical histiocytosis in the lung.
机构信息
Department of Pulmonary diseases, Shanghai Pulmonary Hospital affiliated to Tongji University, Shanghai 200433, China;
出版信息
J Thorac Dis. 2013 Aug;5(4):E124-8. doi: 10.3978/j.issn.2072-1439.2013.07.26.
OBJECTIVE
To report a rare case of atypical histiocytic tumor of the lung with a review of literature.
METHODS
The clinical materials were noted. Literature related to this condition from the past 50 years was reviewed from the group of histiocytic tumors.
RESULTS AND CONCLUSIONS
Clinical manifestations were non-specific. The imaging characteristics of our case were infiltrative lesions with multiple cysts in both lungs. Pathology showed nodular proliferation of atypical cells. Immunohistochemistry suggested a histiocytic origin of the infiltrating atypical cells. Because the pathological findings did not fall into any particular category of typical histiocytic tumors, the final diagnosis was atypical histiocytic tumor. The presentation of atypical histiocytic tumor of the lungs, only, with infiltrative lesions and multiple air cysts seems very rare, with pathological examination being "gold standard" for the diagnosis.
目的
报道 1 例肺非典型组织细胞肿瘤，并复习相关文献。
方法
记载临床资料。从组织细胞肿瘤组中检索过去 50 年与该病相关的文献。
结果与结论
临床表现非特异性。本例影像学特征为双肺浸润性病变伴多发含气囊肿。病理表现为结节状增生的不典型细胞。免疫组化提示浸润性不典型细胞源于组织细胞。由于病理表现未归入任何特定类型的典型组织细胞肿瘤，最终诊断为非典型组织细胞肿瘤。肺部仅表现为浸润性病变伴多发含气囊肿的非典型组织细胞肿瘤极为罕见，病理检查是诊断的“金标准”。
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