氩激光全视网膜光凝术后黄斑中心凹下脉络膜厚度的变化
Change in subfoveal choroidal thickness after argon laser panretinal photocoagulation.
作者信息
Cho Ga Eun, Cho Hee Yun, Kim Yun Taek
机构信息
Department of Ophthalmology, Ewha Womans University School of Medicine, Seoul, Korea.
出版信息
Int J Ophthalmol. 2013 Aug 18;6(4):505-9. doi: 10.3980/j.issn.2222-3959.2013.04.18. eCollection 2013.
AIM
To evaluate changes in subfoveal choroidal thickness (SFCT) and macular thickness as measured by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT) after argon laser panretinal photocoagulation (PRP) in patients with severe diabetic retinopathy.
METHODS
This prospective, comparative case series included 21 patients (28 eyes) with severe diabetic retinopathy. All patients underwent three sessions of PRP. The SFCT and macular thickness were measured using EDI-OCT at baseline and one week after completion of 3 sessions of PRP.
RESULTS
SFCT before PRP was (318.1±96.5)µm and increased to (349.9±108.3)µm (P=0.001) after PRP. Macular thickness significantly increased at one week after PRP (from 273.1±23.9µm at baseline vs 295.8±25.3µm at one week; P<0.001). No significant relationship between the changes in macular thickness and SFCT was observed (r=-0.13, P=0.52).
CONCLUSION
PRP induced increases in both SFCT and macular thickness. Changes in SFCT did not correlate with changes in macular thickness.
目的
评估严重糖尿病视网膜病变患者接受氩激光全视网膜光凝（PRP）后，通过增强深度成像光谱域光学相干断层扫描（EDI-OCT）测量的黄斑中心凹下脉络膜厚度（SFCT）和黄斑厚度的变化。
方法
本前瞻性、比较性病例系列研究纳入了21例（28只眼）严重糖尿病视网膜病变患者。所有患者均接受了3次PRP治疗。在基线时以及完成3次PRP治疗后1周，使用EDI-OCT测量SFCT和黄斑厚度。
结果
PRP治疗前SFCT为（318.1±96.5）μm，PRP治疗后增加至（349.9±108.3）μm（P=0.001）。PRP治疗后1周黄斑厚度显著增加（基线时为273.1±23.9μm，1周时为295.8±25.3μm；P<0.001）。未观察到黄斑厚度变化与SFCT变化之间存在显著相关性（r=-0.13，P=0.52）。
结论
PRP导致SFCT和黄斑厚度均增加。SFCT的变化与黄斑厚度的变化不相关。
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