Yuan Lei, Wang Zhi-Qiang, Zhang Xiao-Li, Cui Xiao-Yan, Kong De-Yin
Department of Urology, Shouguang Hospital of Traditional Chinese Medicine, Weifang, Shandong 262700, China.
Zhonghua Nan Ke Xue. 2013 Aug;19(8):732-5.
To evaluate the clinical efficacy of bladder gasification and stasis dispersion combined with antibiotic therapy in the treatment of III A chronic prostatitis.
We conducted a randomized controlled clinical study on 120 III A prostatitis patients that all met the diagnostic criteria. We divided the patients into groups A, B and C of equal number to receive oral medication of sparfloxacin, sparfloxacin + tamsulosin, and sparfloxacin + herbal decoction, respectively, all for a course of 4 weeks. We evaluated the primary therapeutic indexes according to the total scores of the patients on traditional Chinese medicine (TCM) syndrome and NIH-CPSI and the secondary therapeutic indexes based on the count of white blood cells (WBC) in the expressed prostatic secretion (EPS).
After treatment, the total scores on TCM syndrome and NIH-CPSI were significantly reduced in groups B (42.15 +/- 10.29 and 13.25 +/- 6.04) and C (41.26 +/- 11.25 and 12.38 +/- 7.19) than in A (49.43 +/- 11.09 and 17.62 +/- 5.84) ( P < 0.05), and so was the WBC count in EPS in group C (7.76 +/- 15.73) than in groups A (11.45 +/- 10.33) and B (12.28 +/- 13.81) (P < 0.05). The difference between pre- and post-treatment scores on TCM syndrome was more significant in group C (12.65 +/- 11.76) than in B (8.55 +/- 10.15) (P < 0.05).
Bladder gasification and stasis dispersion combined with antibiotic therapy is effective for the treatment of III A chronic prostatitis, and therefore deserves wide clinical application.
评估膀胱气化化瘀联合抗生素治疗ⅢA 型慢性前列腺炎的临床疗效。
对120例符合诊断标准的ⅢA 型前列腺炎患者进行随机对照临床研究。将患者平均分为A、B、C三组,分别口服司帕沙星、司帕沙星 + 坦索罗辛、司帕沙星 + 中药汤剂,疗程均为4周。依据患者中医证候总积分、美国国立卫生研究院慢性前列腺炎症状指数(NIH-CPSI)评估主要治疗指标,根据前列腺液(EPS)中白细胞(WBC)计数评估次要治疗指标。
治疗后,B组(42.15±10.29和13.25±6.04)和C组(41.26±11.25和12.38±7.19)的中医证候总积分及NIH-CPSI均显著低于A组(49.43±11.09和17.62±5.84)(P<0.05),C组EPS中的WBC计数(7.76±15.73)也低于A组(11.45±10.33)和B组(12.28±13.81)(P<0.05)。C组治疗前后中医证候积分差值(12.65±11.76)大于B组(8.55±10.15)(P<0.05)。
膀胱气化化瘀联合抗生素治疗ⅢA 型慢性前列腺炎疗效显著,值得临床广泛应用。