[银屑病的基因标记]
[The genetic markers of psoriasis].
作者信息
Rakhmatov A B, Chichenina I V, Dizik L I, Bodrova N N
出版信息
Vestn Dermatol Venerol. 1990(5):40-3.
PMID:2402941
Abstract
HLA-A, B, and C antigens were studied in 220 psoriasis patients by Terasaki and McLelland's lymphocytotoxic method. The value of relative risk for HLA-B13 and HLA-B17 antigens was estimated: 5.3 and 7.7, respectively. The detected regularities in histocompatibility antigens distribution suggest that typing of psoriasis patients may help predict, with some certainty, the course of the disease, its pattern, and clinical picture.
摘要
采用寺崎和麦克莱兰的淋巴细胞毒性方法，对220例银屑病患者的HLA - A、B和C抗原进行了研究。估计了HLA - B13和HLA - B17抗原的相对风险值，分别为5.3和7.7。在组织相容性抗原分布中检测到的规律表明，对银屑病患者进行分型可能有助于在一定程度上预测疾病的进程、模式和临床表现。
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