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循环游离 DNA(CCFDNA)在癌症患者血液中的临床应用。

The clinical utilization of circulating cell free DNA (CCFDNA) in blood of cancer patients.

机构信息

Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA.

出版信息

Int J Mol Sci. 2013 Sep 13;14(9):18925-58. doi: 10.3390/ijms140918925.

Abstract

Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.

摘要

循环游离 DNA(CCFDNA)的定性和定量检测可应用于恶性和良性肿瘤的管理。在癌症患者中检测循环 DNA 可能有助于为恶性肿瘤的早期诊断建立 DNA 图谱。本文将讨论从血液中获取、使用和分析 CCFDNA 相关的技术问题。

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本文引用的文献

1
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3
Genetic variants in fas signaling pathway genes and risk of gastric cancer.
Int J Cancer. 2014 Feb 15;134(4):822-31. doi: 10.1002/ijc.28415. Epub 2013 Sep 11.
4
Circulating plasma DNA and DNA integrity in breast cancer patients undergoing neoadjuvant chemotherapy.
Clin Chim Acta. 2013 Oct 21;425:206-11. doi: 10.1016/j.cca.2013.07.027. Epub 2013 Aug 2.
8
DNA methylation contributes to natural human variation.
Genome Res. 2013 Sep;23(9):1363-72. doi: 10.1101/gr.154187.112. Epub 2013 Aug 1.

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