Division of Cancer Research and Training, Department of Internal Medicine, Charles Drew University of Medicine and Science, 1720 East 120th Street, Los Angeles, CA 90059, USA.
Int J Mol Sci. 2013 Sep 13;14(9):18925-58. doi: 10.3390/ijms140918925.
Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms. Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies. The technical issues of obtaining, using, and analyzing CCFDNA from blood will be discussed.
循环游离 DNA(CCFDNA)的定性和定量检测可应用于恶性和良性肿瘤的管理。在癌症患者中检测循环 DNA 可能有助于为恶性肿瘤的早期诊断建立 DNA 图谱。本文将讨论从血液中获取、使用和分析 CCFDNA 相关的技术问题。