Shriners Hospitals for Children, Philadelphia, Pennsylvania.
J Neurosurg Spine. 2013 Dec;19(6):658-63. doi: 10.3171/2013.8.SPINE12816. Epub 2013 Sep 27.
Several studies of the outcomes of patients with adolescent idiopathic scoliosis (AIS) with thoracolumbar and lumbar curves after treatment with posterior pedicle screws have been reported, but most of these studies reported only 2-year follow-up. The authors analyzed the radiographic and clinical outcomes of patients with thoracolumbar and lumbar curves treated with posterior pedicle screws after 5 years of follow-up.
A multicenter database was retrospectively queried to identify patients with AIS who underwent spinal fusion for Lenke 3C, 5C, and 6C curves. Radiographs from the following times were compared: preoperative, first follow-up visit, 1-year follow-up visit, 2-year follow-up visit, and 5-year follow-up visit. Chart review included scoliometer measurements, Scoliosis Research Society (SRS)-22 questionnaires, and complications requiring return to the operating room.
Among 26 patients with Lenke 3C, 5C, and 6C curves, the mean (± SD) age was 14.6 ± 2.1 years. From the time of the preoperative radiographs to the 5-year follow-up radiographs, there was a statistically significant improvement in the mean coronal lumbar Cobb angles (p < 0.0001), and from the time of the first postoperative radiographs to the 5-year follow-up radiographs, the lumbar curve remained stable (p = 0.14). From the time of the preoperative radiographs to the 5-year follow-up radiographs, there was a statistically significant improvement in the mean coronal thoracic Cobb angles (p < 0.0001), and from the time of the first postoperative radiographs to the 5-year follow-up radiographs, the thoracic curve remained stable (p = 0.10). From the first postoperative visit to the 5-year follow-up visit, the thoracic kyphosis (T5-12) remained stable (p = 0.10), and from the time of the preoperative radiographs to the 5-year follow-up radiographs, the lumbar lordosis (T-12 to top of sacrum) remained stable (p = 0.44). From the preoperative visit to the 5-year follow-up visit, the coronal balance improved significantly (p < 0.05) and remained stable from the first postoperative visit to the 5-year follow-up visit (p = 0.20). The SRS-22 total scores improved significantly from before surgery to 5 years after surgery (p < 0.0001). No patients required reoperation because of complications.
Correction of the coronal, sagittal, and axial planes in this cohort of patients was maintained from the first follow-up measurements to 5 years after surgery. In addition, at 5 years after surgery total SRS-22 scores and inclinometer readings were improved from preoperative scores and measurements.
已有多项研究报道了后路椎弓根螺钉治疗青少年特发性脊柱侧凸(AIS)合并胸腰段和腰椎段脊柱侧凸患者的结局,但大多数研究仅报道了 2 年的随访结果。作者分析了后路椎弓根螺钉治疗的胸腰段和腰椎段脊柱侧凸患者在 5 年随访时的影像学和临床结局。
通过回顾性检索多中心数据库,确定接受 Lenke 3C、5C 和 6C 型脊柱侧凸后路融合术的 AIS 患者。比较以下时间点的影像学资料:术前、初次随访、1 年随访、2 年随访和 5 年随访。图表分析包括脊柱侧凸测量仪测量值、脊柱侧凸研究协会(SRS)-22 问卷和需要返回手术室的并发症。
26 例 Lenke 3C、5C 和 6C 型脊柱侧凸患者的平均(±SD)年龄为 14.6±2.1 岁。从术前影像学检查到 5 年随访影像学检查,冠状位腰椎 Cobb 角的平均改善具有统计学意义(p<0.0001),并且从术后第 1 次影像学检查到 5 年随访影像学检查,腰椎侧凸保持稳定(p=0.14)。从术前影像学检查到 5 年随访影像学检查,冠状位胸椎 Cobb 角的平均改善具有统计学意义(p<0.0001),并且从术后第 1 次影像学检查到 5 年随访影像学检查,胸椎侧凸保持稳定(p=0.10)。从术后第 1 次随访到 5 年随访,胸椎后凸(T5-12)保持稳定(p=0.10),从术前影像学检查到 5 年随访影像学检查,腰椎前凸(T-12 至骶骨顶)保持稳定(p=0.44)。从术前到 5 年随访,冠状位平衡显著改善(p<0.05),并且从术后第 1 次随访到 5 年随访保持稳定(p=0.20)。SRS-22 总评分从术前到术后 5 年显著提高(p<0.0001)。无患者因并发症需要再次手术。
在该队列患者中,从第 1 次随访到术后 5 年,冠状位、矢状位和轴向平面的矫正情况保持稳定。此外,术后 5 年,SRS-22 总评分和脊柱侧凸测量仪读数均优于术前。