植物是凝集素的丰富储备。
Plant as a plenteous reserve of lectin.
作者信息
Ingale A G, Hivrale A U
机构信息
Department of Biotechnology; School of Life Sciences; North Maharashtra University; Jalgaon, India.
出版信息
Plant Signal Behav. 2013;8(12):e26595. doi: 10.4161/psb.26595. Epub 2013 Oct 1.
Abstract
Lectins are clusters of glycoproteins of nonimmune foundation that combine specifically and reversibly to carbohydrates, mainly the sugar moiety of glycoconjugates, resulting in cell agglutination and precipitation of glycoconjugates. They are universally distributed in nature, being established in plants, fungi, viruses, bacteria, crustacea, insects, and animals, but leguminacae plants are rich source of lectins. The present review reveals the structure, biological properties, and application of plant lectins.
摘要
凝集素是一类非免疫来源的糖蛋白簇，它们能与碳水化合物（主要是糖缀合物的糖部分）特异性且可逆地结合，从而导致细胞凝集和糖缀合物沉淀。它们在自然界中广泛分布，存在于植物、真菌、病毒、细菌、甲壳类动物、昆虫和动物中，但豆科植物是凝集素的丰富来源。本综述揭示了植物凝集素的结构、生物学特性及应用。
相似文献
1
Plant as a plenteous reserve of lectin.
Plant Signal Behav. 2013;8(12):e26595. doi: 10.4161/psb.26595. Epub 2013 Oct 1.
2
Plant lectins, chemical and biological aspects.
Mem Inst Oswaldo Cruz. 1991;86 Suppl 2:211-8. doi: 10.1590/s0074-02761991000600048.
3
Lectins: cell-agglutinating and sugar-specific proteins.
Science. 1972 Sep 15;177(4053):949-59. doi: 10.1126/science.177.4053.949.
4
Current trends of lectins from microfungi.
Crit Rev Biotechnol. 2011 Sep;31(3):193-210. doi: 10.3109/07388551.2010.505911. Epub 2010 Oct 5.
5
Isolation of a novel plant lectin with an unusual specificity from Calystegia sepium.
Glycoconj J. 1997 Feb;14(2):259-65. doi: 10.1023/a:1018502107707.
6
The interactions of lectins with animal cell surfaces.
Int Rev Cytol. 1974;39:89-190. doi: 10.1016/s0074-7696(08)60939-0.
7
The mechanisms of lectin-mediated cell agglutination.
Pathol Biol (Paris). 1979 Feb;27(2):103-13.
8
SPR studies of carbohydrate-lectin interactions as useful tool for screening on lectin sources.
Biosens Bioelectron. 2007 Jun 15;22(12):2983-8. doi: 10.1016/j.bios.2006.12.021. Epub 2006 Dec 27.
9
Microscopy examination of red blood and yeast cell agglutination induced by bacterial lectins.
PLoS One. 2019 Jul 25;14(7):e0220318. doi: 10.1371/journal.pone.0220318. eCollection 2019.
10
[Inhibitory effect of carbohydrates on the precipitation of human glycoproteins by Pea lectins (author's transl)].
Ann Pharm Fr. 1978;36(11-12):625-30.
引用本文的文献
1
Exploring the biochemical and molecular mechanisms that contribute to Huanglongbing (HLB) tolerance in Citrus australis hybrids.
BMC Genomics. 2025 Aug 19;26(1):761. doi: 10.1186/s12864-025-11942-x.
2
Algal Metabolites Can Be an Immune Booster against COVID-19 Pandemic.
Antioxidants (Basel). 2022 Feb 24;11(3):452. doi: 10.3390/antiox11030452.
3
Cyanobacteria and Algae-Derived Bioactive Metabolites as Antiviral Agents: Evidence, Mode of Action, and Scope for Further Expansion; A Comprehensive Review in Light of the SARS-CoV-2 Outbreak.
Antioxidants (Basel). 2022 Feb 10;11(2):354. doi: 10.3390/antiox11020354.
4
Plant lectins as prospective antiviral biomolecules in the search for COVID-19 eradication strategies.
Biomed Pharmacother. 2022 Feb;146:112507. doi: 10.1016/j.biopha.2021.112507. Epub 2021 Dec 7.
5
Research advances and prospects of legume lectins.
J Biosci. 2021;46(4). doi: 10.1007/s12038-021-00225-8.
6
Algae-Derived Bioactive Molecules for the Potential Treatment of SARS-CoV-2.
Molecules. 2021 Apr 8;26(8):2134. doi: 10.3390/molecules26082134.
7
Tarin, a Potential Immunomodulator and COX-Inhibitor Lectin Found in Taro ().
Compr Rev Food Sci Food Saf. 2018 Jul;17(4):878-891. doi: 10.1111/1541-4337.12358. Epub 2018 May 10.
8
Engineering of a Lectibody Targeting High-Mannose-Type Glycans of the HIV Envelope.
Mol Ther. 2019 Nov 6;27(11):2038-2052. doi: 10.1016/j.ymthe.2019.07.021. Epub 2019 Aug 9.
9
Potent antiviral activity of carbohydrate-specific algal and leguminous lectins from the Brazilian biodiversity.
Medchemcomm. 2019 Jan 14;10(3):390-398. doi: 10.1039/c8md00508g. eCollection 2019 Mar 1.
10
Functional characterization of chitin-binding lectin from Solanum integrifolium containing anti-fungal and insecticidal activities.
BMC Plant Biol. 2018 Jan 3;18(1):3. doi: 10.1186/s12870-017-1222-0.
本文引用的文献
1
Potential role of lipoxygenases in defense against insect herbivory.
J Chem Ecol. 1994 Mar;20(3):651-66. doi: 10.1007/BF02059605.
2
A lectin with anti-HIV-1 reverse transcriptase, antitumor, and nitric oxide inducing activities from seeds of Phaseolus vulgaris cv. extralong autumn purple bean.
J Agric Food Chem. 2010 Feb 24;58(4):2221-9. doi: 10.1021/jf903964u.
3
A lectin isolated from bananas is a potent inhibitor of HIV replication.
J Biol Chem. 2010 Mar 19;285(12):8646-55. doi: 10.1074/jbc.M109.034926. Epub 2010 Jan 15.
4
Control of Root-knot Nematodes on Tomato by Lectins.
J Nematol. 1987 Jul;19(3):331-5.
5
Mannose-binding lectin from yam (Dioscorea batatas) tubers with insecticidal properties against Helicoverpa armigera (Lepidoptera: Noctuidae).
J Agric Food Chem. 2009 Apr 8;57(7):2896-902. doi: 10.1021/jf8040269.
6
Musa acuminata (Del Monte banana) lectin is a fructose-binding lectin with cytokine-inducing activity.
Phytomedicine. 2009 Jun;16(6-7):594-600. doi: 10.1016/j.phymed.2008.12.016. Epub 2009 Feb 4.
7
Purification and characterization of a novel lectin from the toxic wild mushroom Inocybe umbrinella.
Toxicon. 2009 Mar 1;53(3):360-6. doi: 10.1016/j.toxicon.2008.12.009. Epub 2008 Dec 14.
8
Insecticidal action of PF2 lectin from Olneya tesota (Palo Fierro) against Zabrotes subfasciatus larvae and midgut glycoconjugate binding.
J Agric Food Chem. 2009 Jan 28;57(2):689-94. doi: 10.1021/jf802557m.
9
Specific Precipitating Activity of Plant Agglutinins (Lectins).
Science. 1954 Mar 26;119(3091):419. doi: 10.1126/science.119.3091.419.
10
Lectins: a possible basis for specificity in the Rhizobium--legume root nodule symbiosis.
Science. 1974 Jul 19;185(4147):269-71. doi: 10.1126/science.185.4147.269.
Zotero 插件