Morant-Talamante Nuria, Diez-Domingo Javier, Martínez-Úbeda Sergio, Puig-Barberá Joan, Alemán-Sánchez Sara, Pérez-Breva Lina
Vaccine Research Area, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region FISABIO - Public Health, Valencia, Spain.
BMC Infect Dis. 2013 Oct 5;13:463. doi: 10.1186/1471-2334-13-463.
Epidemiologic data of Herpes Zoster (HZ) disease in Spain are scarce. The objective of this study was to assess the epidemiology of HZ in the Valencian Community (Spain), using outpatient and hospital electronic health databases.
Data from 2007 to 2010 was collected from computerized health databases of a population of around 5 million inhabitants. Diagnoses were recorded by physicians using the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM). A sample of medical records under different criteria was reviewed by a general practitioner, to assess the reliability of codification.
The average annual incidence of HZ was 4.60 per 1000 persons-year (PY) for all ages (95% CI: 4.57-4.63), is more frequent in women [5.32/1000PY (95% CI: 5.28-5.37)] and is strongly age-related, with a peak incidence at 70-79 years. A total of 7.16/1000 cases of HZ required hospitalization.
Electronic health database used in the Valencian Community is a reliable electronic surveillance tool for HZ disease and will be useful to define trends in disease burden before and after HZ vaccine introduction.
西班牙带状疱疹(HZ)疾病的流行病学数据匮乏。本研究的目的是利用门诊和医院电子健康数据库评估西班牙巴伦西亚自治区HZ的流行病学情况。
从约500万居民的计算机化健康数据库中收集2007年至2010年的数据。医生使用《国际疾病分类》第九版临床修订本(ICD-9-CM)记录诊断情况。一名全科医生按照不同标准对一份病历样本进行了审查,以评估编码的可靠性。
所有年龄段HZ的年均发病率为每1000人年4.60例(95%可信区间:4.57 - 4.63),在女性中更为常见[5.32/1000人年(95%可信区间:5.28 - 5.37)],且与年龄密切相关,发病率在70 - 79岁达到峰值。每1000例HZ病例中有7.16例需要住院治疗。
巴伦西亚自治区使用的电子健康数据库是一种用于HZ疾病的可靠电子监测工具,将有助于确定引入HZ疫苗前后疾病负担的趋势。