一项关于将飞秒激光脉冲聚焦于眼内介质以用于眼科手术的体外研究。
An in vitro study on focusing fs-laser pulses into ocular media for ophthalmic surgery.
作者信息
Merker Marina, Ackermann Roland, Kammel Robert, Kunert Kathleen S, Nolte Stefan
机构信息
Institute of Applied Physics, Abbe Center of Photonics, Friedrich-Schiller-Universität Jena, Max-Wien-Platz 1, Jena, 07743, Germany; Faculty SciTec, Ernst-Abbe-Fachhochschule Jena, Carl-Zeiß-Promenade 2, Jena, 07745, Germany.
出版信息
Lasers Surg Med. 2013 Nov;45(9):589-96. doi: 10.1002/lsm.22179. Epub 2013 Sep 17.
BACKGROUND AND OBJECTIVE
To investigate femtosecond (fs)-laser patterns within ocular media for ophthalmic surgery.
METHODS
Vitreous and crystalline lens tissue from porcine eyes were treated with 2-dimensional fs-laser patterns and inspected under the optical microscope. Time resolved pump-probe experiments were conducted on vitreous tissue and gelatin, which should act as a model for crystalline lens tissue.
RESULTS
Within crystalline lens tissue, pulse overlap leads to the formation of large bubbles, which is caused by subsequent energy input from the surrounding plasma channel. This effect can be used for bubble size control. Vitreous tissue behaves similar to water under fs-laser treatment, but it still allows fs-laser cutting.
CONCLUSION
Bubble size control by laser bursts may reduce optical side-effects of fs-laser treatment. Furthermore, fs-laser treatment could be used for vitreoretinal applications.
背景与目的
研究眼科手术中眼内介质内的飞秒（fs）激光模式。
方法
用二维飞秒激光模式处理猪眼的玻璃体和晶状体组织，并在光学显微镜下检查。对玻璃体组织和明胶（其作为晶状体组织的模型）进行时间分辨泵浦 - 探测实验。
结果
在晶状体组织内，脉冲重叠导致形成大气泡，这是由周围等离子体通道的后续能量输入引起的。这种效应可用于控制气泡大小。在飞秒激光处理下，玻璃体组织的行为类似于水，但它仍然允许飞秒激光切割。
结论
通过激光脉冲控制气泡大小可能会减少飞秒激光治疗的光学副作用。此外，飞秒激光治疗可用于玻璃体视网膜应用。
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