Koebnick Corinna, Black Mary Helen, Wu Jun, Martinez Mayra P, Smith Ning, Kuizon Beatriz, Cuan David, Young Deborah Rohm, Lawrence Jean M, Jacobsen Steven J
Department of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, CA.
J Clin Hypertens (Greenwich). 2013 Nov;15(11):793-805. doi: 10.1111/jch.12199. Epub 2013 Oct 10.
In the absence of evidence-based guidelines for high blood pressure screening in asymptomatic youth, a reasonable strategy is to screen those who are at high risk. The present study aimed to identify optimal body mass index (BMI) thresholds as a marker for high-risk youth to predict hypertension prevalence. In a cross-sectional study, youth aged 6 to 17 years (n=237,248) enrolled in an integrated prepaid health plan in 2007 to 2009 were classified according to their BMI and hypertension status. In moderately and extremely obese youth, the prevalence of hypertension was 3.8% and 9.2%, respectively, compared with 0.9% in normal weight youth. The adjusted prevalence ratios (95% confidence intervals) of hypertension for normal weight, overweight, moderate obesity, and extreme obesity were 1.00 (Reference), 2.27 (2.08-2.47), 4.43 (4.10-4.79), and 10.76 (9.99-11.59), respectively. The prevalence of hypertension was best predicted by a BMI-for-age ≥94th percentile. These results suggest that all obese youth should be screened for hypertension.
在缺乏针对无症状青少年高血压筛查的循证指南的情况下,一个合理的策略是对那些高危青少年进行筛查。本研究旨在确定最佳体重指数(BMI)阈值,作为预测高血压患病率的高危青少年的一个标志物。在一项横断面研究中,2007年至2009年参加综合预付健康计划的6至17岁青少年(n = 237,248)根据其BMI和高血压状况进行分类。在中度和极度肥胖的青少年中,高血压患病率分别为3.8%和9.2%,而正常体重青少年中的患病率为0.9%。正常体重、超重、中度肥胖和极度肥胖青少年高血压的校正患病率比(95%置信区间)分别为1.00(参考值)、2.27(2.08 - 2.47)、4.43(4.10 - 4.79)和10.76(9.99 - 11.59)。年龄别BMI≥第94百分位数对高血压患病率的预测效果最佳。这些结果表明,所有肥胖青少年都应接受高血压筛查。