Departments of Infectious Diseases and Avian Diseases; and.
Poult Sci. 2013 Nov;92(11):2886-91. doi: 10.3382/ps.2013-03331.
The genetic organization of the 24 duck circovirus (DuCV) strains detected in commercial Pekin ducks from South Korea between 2011 and 2012 is described in this study. Multiple sequence alignment and phylogenetic analyses were performed on the 24 viral genome sequences as well as on 45 genome sequences available from the GenBank database. Phylogenetic analyses based on the genomic and open reading frame 2/cap sequences demonstrated that all DuCV strains belonged to genotype 1 and were designated in a subcluster under genotype 1. Analysis of the capsid protein amino acid sequences of the 24 Korean DuCV strains showed 10 substitutions compared with that of other genotype 1 strains. Our analysis showed that genotype 1 is predominant and circulating in South Korea. These present results serve as incentive to add more data to the DuCV database and provide insight to conduct further intensive study on the geographic relationships among these virus strains.
本研究描述了 2011 年至 2012 年期间在韩国商业养殖的北京鸭中检测到的 24 株鸭圆环病毒(DuCV)的遗传组织。对 24 个病毒基因组序列以及来自 GenBank 数据库的 45 个基因组序列进行了多序列比对和系统进化分析。基于基因组和开放阅读框 2/衣壳序列的系统进化分析表明,所有 DuCV 株均属于基因型 1,并在基因型 1 下的一个亚群中进行了指定。对 24 株韩国 DuCV 株的衣壳蛋白氨基酸序列分析显示,与其他基因型 1 株相比,有 10 个取代。本分析表明,基因型 1 是优势和循环在韩国。这些结果表明需要向 DuCV 数据库中添加更多数据,并深入研究这些病毒株之间的地理关系。