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脆质支原体:从生物学到致病性。

Waddlia chondrophila: from biology to pathogenicity.

机构信息

Institute of Microbiology, University Hospital Center and University of Lausanne, Lausanne, Switzerland.

出版信息

Microbes Infect. 2013 Dec;15(14-15):1033-41. doi: 10.1016/j.micinf.2013.09.010. Epub 2013 Oct 18.

Abstract

Waddlia chondrophila is an emerging pathogen causing miscarriages in humans and abortions in ruminants. The full genome of this Chlamydia-related bacterium has been recently completed, providing new insights into its biology and evolution. Moreover, new cell biology approaches and the use of novel inhibitors have allowed detailed investigations of its interaction with host cells.

摘要

脆质支原体是一种新兴的病原体,可导致人类流产和反刍动物流产。该衣原体相关细菌的全基因组最近已完成测序,为其生物学和进化提供了新的见解。此外,新的细胞生物学方法和新型抑制剂的使用,使得对其与宿主细胞相互作用的详细研究成为可能。

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