1 Department of Radiology, Northwestern Memorial Hospital, Northwestern University-Feinberg School of Medicine, 676 N Saint Clair St, Ste 800, Chicago, IL 60611.
AJR Am J Roentgenol. 2013 Nov;201(5):1075-82. doi: 10.2214/AJR.12.10354.
The purpose of this study was intrapatient comparison of image quality and radiation dose between MDCT scans of the chest, abdomen, and pelvis obtained with attenuation-based automated kilovoltage selection and sinogram-affirmed iterative reconstruction and scans obtained with standard kilovoltage selection and a filtered backprojection image reconstruction algorithm.
One hundred one oncology patients who had undergone two chest, abdominal, and pelvis CT scans within 1 year were imaged with standard tube voltage selection of 120 kVp using a filtered backprojection reconstruction algorithm (protocol 1) and with attenuation-based automated tube voltage selection using an iterative reconstruction algorithm (protocol 2). Radiation dose parameters (volumetric CT dose index [CTDIvol], dose-length product, and effective dose) as well as image noise, signal-to-noise ratio, and contrast-to-noise ratio were compared. Two independent radiologists evaluated image quality and sharpness. Student t test, Fisher exact test, and Wilcoxon signed-rank test were used for analysis. A p value less than 0.05 was considered significant.
Mean ± SD CTDIvol values were 19.9 ± 4.43 mGy and 12.53 ± 4.79 mGy for protocols 1 and 2, respectively (p < 0.0001). Effective dose was 38.2% lower on average using protocol 2 compared with protocol 1 (12.08 vs 19.55 mSv; p < 0.0001). Objective image quality parameters were significantly better in protocol 2 (p < 0.0001). Both radiologists found the overall image quality and sharpness to be similar for both protocols (p > 0.05).
In patients undergoing CT examination of the chest, abdomen, and pelvis, the combination of attenuation-based automated tube voltage selection with iterative reconstruction significantly reduced radiation dose parameters and maintained objective image quality when compared with standard tube voltage selection associated with filtered backprojection reconstruction.
本研究旨在对基于衰减的自动千伏选择和正弦图确认迭代重建的胸部、腹部和骨盆 MDCT 扫描与使用标准千伏选择和滤波反投影图像重建算法的扫描进行患者内比较,以比较图像质量和辐射剂量。
101 例在 1 年内接受过两次胸部、腹部和骨盆 CT 扫描的肿瘤患者,使用滤波反投影重建算法(方案 1)以标准管电压选择 120 kVp 进行成像,并使用基于衰减的自动管电压选择使用迭代重建算法(方案 2)。比较了辐射剂量参数(容积 CT 剂量指数 [CTDIvol]、剂量长度乘积和有效剂量)以及图像噪声、信噪比和对比噪声比。两名独立的放射科医生评估了图像质量和锐度。使用学生 t 检验、Fisher 确切检验和 Wilcoxon 符号秩检验进行分析。p 值小于 0.05 被认为具有统计学意义。
方案 1 和 2 的平均 ± SD CTDIvol 值分别为 19.9 ± 4.43 mGy 和 12.53 ± 4.79 mGy(p < 0.0001)。与方案 1 相比,方案 2 的平均有效剂量降低了 38.2%(12.08 与 19.55 mSv;p < 0.0001)。方案 2 的客观图像质量参数明显更好(p < 0.0001)。两位放射科医生均发现两种方案的整体图像质量和锐度相似(p > 0.05)。
在接受胸部、腹部和骨盆 CT 检查的患者中,与标准管电压选择相关联的滤波反投影重建相比,基于衰减的自动管电压选择与迭代重建的组合可显著降低辐射剂量参数并保持客观图像质量。