Salahuddin Omer, Azhar Muhammad, Imtiaz Aqsa, Latif Munawer
Department of Plastic Surgery, Shifa International Hospital, Islamabad, Pakistan.
Diabet Foot Ankle. 2013 Oct 21;4. doi: 10.3402/dfa.v4i0.22477. eCollection 2013.
To evaluate the functional outcome, morbidity, and viability of foot salvage in diabetic patients.
This prospective case series was conducted from March 2007 to December 2012 at the department of surgery Pakistan Ordnance Factories Hospital, Wah Cantt, Pakistan. 123 males and 26 female patients were included in the study. All the patients were treated after getting admitted in the hospital and wounds were managed with daily dressings, nursing care and debridement of necrotic tissue with adequate antibiotic coverage.
In total, 149 patients (mean age: 56±7.52 years) with 171 amputations were included in the study. The mean duration of diabetes mellitus (DM) was 9±4.43 years. Ninety-seven percent of the patients were diagnosed with type 2 DM. Wound debridement was performed under general anesthesia in 48 (33.2%) patients, whereas local anesthesia was used for the rest of the patients after having good glycemic control and improvement in general health. The most common pathogen isolated from the infected wounds was Staphylococcus aureus in approximately 46% cases. Regarding the types of amputation, partial toe amputation was performed in 21 (12.2%) cases, second-toe amputation in 60 (35%) cases, hallux amputation in 41 (24%) cases, multiple toe amputations in 29 (17%) cases, bilateral feet involvement was observed in 16 (9.3%) cases, and transmetatarsal amputation was performed in 4 (2.3%) cases. The wounds healed well except in 19 cases where amputation had to be revised to a more proximal level. Thirty-nine patients died during the study period: 3 died of wound-related complications and 36 died of systemic complications.
With the ever-increasing epidemic of DM, the number of patients with diabetic foot ulcers has also significantly risen. Early surgical management with good glycemic control and foot care with close monitoring can decrease amputations and thus foot salvage can be successfully achieved.
评估糖尿病患者足部挽救的功能结局、发病率及存活率。
本前瞻性病例系列研究于2007年3月至2012年12月在巴基斯坦瓦赫坎特巴基斯坦兵工厂医院外科进行。研究纳入了123例男性和26例女性患者。所有患者入院后接受治疗,伤口通过每日换药、护理以及在充分使用抗生素的情况下对坏死组织进行清创处理。
本研究共纳入149例患者(平均年龄:56±7.52岁),共进行了171次截肢手术。糖尿病(DM)的平均病程为9±4.43年。97%的患者被诊断为2型糖尿病。48例(33.2%)患者在全身麻醉下进行伤口清创,其余患者在血糖得到良好控制且一般健康状况有所改善后采用局部麻醉。从感染伤口分离出的最常见病原体约46%为金黄色葡萄球菌。关于截肢类型,21例(12.2%)进行了部分趾截肢,60例(35%)进行了第二趾截肢,41例(24%)进行了拇趾截肢,29例(17%)进行了多趾截肢,16例(9.3%)观察到双侧足部受累,4例(2.3%)进行了经跖骨截肢。除19例伤口愈合不佳需将截肢部位改为更靠近近端水平外,其余伤口愈合良好。39例患者在研究期间死亡:3例死于伤口相关并发症,36例死于全身并发症。
随着糖尿病流行情况日益严重,糖尿病足溃疡患者数量也显著增加。早期手术治疗、良好的血糖控制以及密切监测下的足部护理可减少截肢,从而成功实现足部挽救。