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在临床诊断的急性卒中中识别疑似卒中病例。

Identification of stroke mimics among clinically diagnosed acute strokes.

作者信息

Tuntiyatorn Lojana, Saksornchai Pichaya, Tunlayadechanont Supoch

机构信息

Division of Neuroradiology, Department of Radiology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

J Med Assoc Thai. 2013 Sep;96(9):1191-8.

Abstract

BACKGROUND

Stroke is a clinically syndrome of a sudden onset of neurological deficit in a vascular cause. Stroke mimics is the non-vascular disorders with stroke-like clinical symptoms. It is important to distinguish true stroke from mimics since treatment plan may differ

OBJECTIVE

To determine the incidence of the stroke mimics and identify their etiologies.

MATERIAL AND METHOD

All non-contrast head CT of the patients with clinically diagnosed stroke who immediately received imaging upon arrival at the emergency department of the university hospital were retrospectively reviewed in 12-month period between January 1 and December 31, 2008. Medical records, laboratory results, MRI, and 6-month clinical follow-up records were reviewed for final diagnosis.

RESULTS

Seven hundred four patients were included in this study, including 363 (51.5%) men and 341 (48.5%) women with range in age from 24 to 108 years. Amongst those, 417 (59.2%) were ischemic stroke, 80 (11.40%) were hemorrhagic stroke, 186 (26.4%) were stroke-mimics, and 21 (3%) were inconclusive. The etiologies among stroke-mimics were metabolic/intoxication (35, 18.8%), sepsis (28, 15.0%), seizure (21, 11.3%), syncope (20, 10.8%), subdural hemorrhage (14, 7.5%), vertigo (11, 6.0%), brain tumor (10, 5.30%), central nervous system infection (5, 2.7%), others (26, 14.0%), and unspecified (16, 8.6%).

CONCLUSION

Incidence rates and etiologies of the stroke mimics were similar to the western reports. However the frequency of each mimic was not.

摘要

背景

中风是一种由血管原因导致的突然出现神经功能缺损的临床综合征。类中风是具有类似中风临床症状的非血管性疾病。区分真正的中风与类中风很重要,因为治疗方案可能不同。

目的

确定类中风的发病率并明确其病因。

材料与方法

对2008年1月1日至12月31日这12个月期间,在大学医院急诊科就诊时立即接受影像学检查且临床诊断为中风的患者的所有非增强头部CT进行回顾性分析。查阅病历、实验室检查结果、磁共振成像(MRI)以及6个月的临床随访记录以做出最终诊断。

结果

本研究共纳入704例患者,其中男性患者363例(51.5%),女性患者341例(48.5%),年龄范围为24至108岁。其中,缺血性中风417例(59.2%),出血性中风80例(11.40%),类中风186例(26.4%),不确定病例21例(3%)。类中风的病因包括代谢/中毒(35例,18.8%)、败血症(28例,15.0%)、癫痫发作(21例,11.3%)、晕厥(20例,10.8%)、硬膜下出血(14例,7.5%)、眩晕(11例,6.0%)、脑肿瘤(10例,5.30%)、中枢神经系统感染(5例,2.7%)、其他(26例,14.0%)以及未明确的病因(16例,8.6%)。

结论

类中风的发病率和病因与西方报道相似。然而,每种类中风的发生频率并非如此。

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