Guillon Benoît, Maiga Youssoufa, Desal Hubert
Unité neurovasculaire, hôpital G. R. Laennec, CHU de Nantes, 44093 Nantes Cedex 1, France.
Rev Prat. 2013 Sep;63(7):939-40, 942-6.
Cervical and intracranial artery dissections result from the occurrence of an intramural hematoma. Arterial dissection is one of the main causes of ischemic stroke in young adults. Pathophysiology remains misunderstood but probably results from the association of a triggering environmental factor with an underlying arteriopathy. Usually, headache or neck pain, sometimes associated with local signs (e.g., Horner's sign) occurs after a trivial trauma, followed some hours or days later by cerebral infarct. Diagnosis may be confirmed by CT-scan or MRI with angiogram. In the absence of randomized studies, acute treatment of cervical artery dissection is based on antithrombotics. IV thrombolysis is recommended in acute stroke. Outcome is favorable in most cases, related to infarct severity. Recurrences are very rare.
颈内动脉和颅内动脉夹层是由壁内血肿的出现引起的。动脉夹层是年轻成年人缺血性卒中的主要原因之一。其病理生理学仍未完全明了,但可能是由触发环境因素与潜在的动脉病变共同作用所致。通常,在轻微创伤后会出现头痛或颈部疼痛,有时伴有局部体征(如霍纳氏征),数小时或数天后会继发脑梗死。CT扫描或MRI血管造影可确诊。由于缺乏随机对照研究,颈内动脉夹层的急性治疗以抗栓治疗为主。急性卒中推荐静脉溶栓治疗。在大多数情况下,预后良好,与梗死严重程度有关。复发非常罕见。