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超声引导下对接受会阴尿道造口术的猫进行阴部神经阻滞:一项前瞻性、随机、研究者盲法、安慰剂对照的临床试验。

Ultrasound-guided pudendal nerve block in cats undergoing perineal urethrostomy: a prospective, randomised, investigator-blind, placebo-controlled clinical trial.

作者信息

Adami Chiara, Dayer Thomas, Spadavecchia Claudia, Angeli Giovanni

机构信息

1Department of Veterinary Clinical Science, Anaesthesiology and Pain Therapy Division, Vetsuisse Faculty, University of Berne, Berne, Switzerland.

出版信息

J Feline Med Surg. 2014 Apr;16(4):340-5. doi: 10.1177/1098612X13509082. Epub 2013 Oct 30.

Abstract

The objective of this study was to evaluate the clinical usefulness, in terms of analgesic efficacy and safety, of ultrasound-guided pudendal nerve block performed with bupivacaine in cats undergoing perineal urethrostomy. Eighteen client-owned male cats scheduled for perineal urethrostomy were enrolled in the study and assigned to one of two treatment groups. The pudendal nerve block was performed under general anaesthesia, as described elsewhere, with 0.3 ml/kg of either saline (group C) or 0.5% bupivacaine (group B) - the total injection volume being split equally between the two sites of injection (left and right). Intra-operatively, assessment of nociception was based on the rescue analgesics requirement, as well as on the evaluation of changes in physiological parameters in comparison with the baseline values. Postoperative pain assessment was performed using three different pain scales at recovery and then 1, 2 and 3 h after recovery. Cats in group B showed lower heart rates and required fewer analgesics during surgery than group C. Postoperatively, group B had lower pain scores and needed less rescue buprenorphine than group C. Iatrogenic block-related complications were not observed. In conclusion, the ultrasound-guided pudendal nerve block can be considered clinically useful in feline medicine as it provides reliable analgesia in cats undergoing perineal urethrostomy.

摘要

本研究的目的是评估在接受会阴尿道造口术的猫中,使用布比卡因进行超声引导下阴部神经阻滞在镇痛效果和安全性方面的临床实用性。18只预定接受会阴尿道造口术的客户拥有的雄性猫被纳入研究,并被分配到两个治疗组之一。阴部神经阻滞在全身麻醉下进行,方法如其他地方所述,分别注射0.3 ml/kg的生理盐水(C组)或0.5%布比卡因(B组),总注射量在两个注射部位(左侧和右侧)平均分配。术中,伤害感受的评估基于急救镇痛药的需求,以及与基线值相比生理参数变化的评估。术后疼痛评估在恢复时以及恢复后1、2和3小时使用三种不同的疼痛量表进行。B组猫在手术期间的心率较低,所需的镇痛药比C组少。术后,B组的疼痛评分较低,所需的急救丁丙诺啡比C组少。未观察到与医源性阻滞相关的并发症。总之,超声引导下阴部神经阻滞在猫科医学中可被认为具有临床实用性,因为它能为接受会阴尿道造口术的猫提供可靠的镇痛。

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