Costa O, Pinatel K, Monier J C
J Rheumatol. 1985 Oct;12(5):928-33.
The natural and synthetic antiribonucleic acid antibodies (anti-RNA) are more frequently found in systemic lupus erythematosus (SLE) (80%) than in systemic sclerosis (66%) or in rheumatoid arthritis (RA) (54.5%). SLE sera contain antibodies directed against a broader variety of RNA than systemic sclerosis sera and most RA sera. Fifty-two percent of SLE and 29.2% of systemic sclerosis sera recognized at least 5 of the 7 RNA types studied, whereas RA sera recognized only one or 2. Synthetic antipolynucleotide antibody activities are mainly antipolyriboguanylic-ribocytidylic acid (prG-rC), antipolyriboadenylic-ribouridylic acid (prA-rU) and polyriboadenylic acid (prA) antibody in SLE, antipolyriboguanylic acid (prG) and antipolyribocytidylic acid (prC) antibody in systemic sclerosis and anti-prG-rC, anti-prC antibody in RA.
天然和合成抗核糖核酸抗体（抗RNA）在系统性红斑狼疮（SLE）（80%）中比在系统性硬化症（66%）或类风湿性关节炎（RA）（54.5%）中更常见。与系统性硬化症血清和大多数RA血清相比，SLE血清含有针对更广泛种类RNA的抗体。52%的SLE血清和29.2%的系统性硬化症血清识别所研究的7种RNA类型中的至少5种，而RA血清仅识别1种或2种。合成抗多核苷酸抗体活性在SLE中主要是抗聚核糖鸟苷酸-核糖胞苷酸（prG-rC）、抗聚核糖腺苷酸-核糖尿苷酸（prA-rU）和聚核糖腺苷酸（prA）抗体，在系统性硬化症中是抗聚核糖鸟苷酸（prG）和抗聚核糖胞苷酸（prC）抗体，在RA中是抗prG-rC、抗prC抗体。
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