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生长抑素受体分子影像学在颅内转移性血管外皮细胞瘤中的应用。

Somatostatin receptor molecular imaging for metastatic intracranial hemangiopericytoma.

机构信息

From the *Department of Radiology, †Section on Hematology and Oncology, Department of Internal Medicine, and ‡Department of Neurosurgery, Wake Forest School of Medicine, Winston-Salem, NC.

出版信息

Clin Nucl Med. 2013 Dec;38(12):984-7. doi: 10.1097/RLU.0000000000000237.

Abstract

Intracranial hemangiopericytomas (HPCs) are rare tumors that closely mimic meningiomas. However, in contrast to meningiomas, HPCs have a relatively high incidence of local recurrence and distant metastases, manifesting the need for sensitive noninvasive methods of detection that efficiently image the entire body. We present a rare case of a right optic nerve sheath HPC in which we identified a previously unknown distant metastasis in the thoracic spine on an 111In-pentetreotide scan. We detail the radiologic characteristics seen with somatostatin receptor imaging, FDG PET, and MRI and discuss how to exploit these findings to detect recurrence and metastatic disease in HPC.

摘要

颅内血管外皮细胞瘤(HPCs)是一种罕见的肿瘤,与脑膜瘤非常相似。然而,与脑膜瘤不同的是,HPC 具有相对较高的局部复发和远处转移率,因此需要能够敏感地无创性检测全身的方法。我们报告了一例罕见的右侧视神经鞘 HPC 病例,在 111In-喷曲肽扫描中发现了以前未知的胸椎远处转移。我们详细描述了生长抑素受体成像、FDG PET 和 MRI 所见的放射学特征,并讨论了如何利用这些发现来检测 HPC 的复发和转移疾病。

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