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未检测到单纯腭裂与人类白细胞抗原(HLA)抗原之间的关联。

Failure to detect association of isolated cleft palate with HLA antigens.

作者信息

Pairitz G, Erickson R P, Schultz J, Sing C F

出版信息

J Immunogenet. 1985 Aug-Oct;12(4-5):259-62. doi: 10.1111/j.1744-313x.1985.tb00853.x.

Abstract

HLA antigen frequencies have been determined in 282 controls and in 33 individuals with isolated cleft palate or the related birth defect velopharyngeal incompetence. No association of particular HLA antigens with this birth defect was found. A previously reported association of HLA A2 with cleft palate, in males, was not confirmed.

摘要

已测定282名对照者以及33名患有孤立性腭裂或相关出生缺陷腭咽功能不全者的HLA抗原频率。未发现特定HLA抗原与该出生缺陷之间存在关联。先前报道的男性中HLA A2与腭裂的关联未得到证实。

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