GGZ inGeest, Amsterdam, The Netherlands ; Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands ; EMGO Institute, VU University Medical Center, Amsterdam, The Netherlands ; PsyQ, Parnassiagroep, The Hague, The Netherlands.
Eur J Psychotraumatol. 2013 Nov 6;4. doi: 10.3402/ejpt.v4i0.21171. eCollection 2013.
In the empirical and clinical literature, complex posttraumatic stress disorder (PTSD) and personality disorders (PDs) are suggested to be predictive of drop-out or reduced treatment effectiveness in trauma-focused PTSD treatment.
In this study, we aimed to investigate if personality characteristics would predict treatment compliance and effectiveness in stabilizing complex PTSD treatment.
In a randomized controlled trial on a 20-week stabilizing group cognitive behavioral treatment (CBT) for child-abuse-related complex PTSD, we included 71 patients of whom 38 were randomized to a psycho-educational and cognitive behavioral stabilizing group treatment. We compared the patients with few PD symptoms (adaptive) (N=14) with the non-adaptive patients (N=24) as revealed by a cluster analysis.
We found that non-adaptive patients compared to the adaptive patients showed very low drop-out rates. Both non-adaptive patients, classified with highly different personality profiles "withdrawn" and "aggressive," were equally compliant. With regard to symptom reduction, we found no significant differences between subtypes. Post-hoc, patients with a PD showed lower drop-out rates and higher effect sizes in terms of complex PTSD severity, especially on domains that affect regulation and interpersonal problems.
Contrary to our expectations, these preliminary findings indicate that this treatment is well tolerated by patients with a variety of personality pathology. Larger sample sizes are needed to study effectiveness for subgroups of complex PTSD patients.
在实证和临床文献中,复杂创伤后应激障碍(PTSD)和人格障碍(PD)被认为是创伤聚焦 PTSD 治疗中辍学或治疗效果降低的预测因素。
本研究旨在探讨人格特征是否能预测稳定复杂 PTSD 治疗中的治疗依从性和疗效。
在一项针对与儿童虐待相关的复杂 PTSD 的为期 20 周的稳定群体认知行为治疗(CBT)的随机对照试验中,我们纳入了 71 名患者,其中 38 名被随机分配到心理教育和认知行为稳定群体治疗中。我们通过聚类分析比较了具有较少 PD 症状(适应性)(N=14)的患者与非适应性患者(N=24)。
我们发现,与适应性患者相比,非适应性患者的辍学率非常低。被归类为具有高度不同人格特征“孤僻”和“攻击性”的非适应性患者同样具有依从性。关于症状减轻,我们没有发现亚型之间有显著差异。事后分析表明,PD 患者的辍学率较低,复杂 PTSD 严重程度的效应量较高,尤其是在影响调节和人际关系问题的领域。
与我们的预期相反,这些初步发现表明,这种治疗方法被各种人格病理的患者很好地耐受。需要更大的样本量来研究复杂 PTSD 患者亚组的疗效。