FRACP, Department of Pediatrics, University of Otago Christchurch, PO Box 4345, Christchurch 8140, New Zealand.
Pediatrics. 2013 Dec;132(6):e1521-8. doi: 10.1542/peds.2013-2024. Epub 2013 Nov 18.
To assess the early adult health, education, and social functioning of a national cohort of very low birth weight (VLBW) infants born in 1986 in New Zealand compared with a control group of young adults born the same year. The impact of neurodevelopmental disability at age 7 to 8 years on young adult outcomes was examined.
Participants underwent a comprehensive face-to-face interview that included standardized assessment tools and previously used custom written survey items.
We interviewed 230 VLBW young adults (71% of survivors) and 69 controls at age 22 to 23 years. VLBW young adults were 5.6 kg lighter and 4.2 cm shorter than controls, had lower rates of tertiary education/training (percentage difference [95% confidence interval]: -13.1 [-21.6 to -1.8]) and university degree completion (-15.6 [-28.0 to -4.8]), had more often been welfare dependent (23.5 [10.2 to 35.0]), had few or no friends (20.5 [7.2 to 32.2]), and more often had wheeze in the past year (20.1 [9.0 to 28.6]). However, in many areas there were no differences between the VLBW cohort and controls, and VLBW adults rated their overall quality of life and behavioral functioning similarly to their peers. Those with previous disability had poorer social, occupational, and physical functioning than other VLBW young adults.
Despite some evidence of health, educational, and social difficulties, former VLBW young adults obtained similar scores across many aspects of health and social functioning as their same age peers, with some differences largely confined to those with previous disability.
评估 1986 年在新西兰出生的极低出生体重(VLBW)婴儿与同年出生的对照组年轻成年人的早期成人健康、教育和社会功能。研究了 7 至 8 岁时神经发育障碍对年轻成年人结局的影响。
参与者接受了全面的面对面访谈,其中包括标准化评估工具和之前使用的自定义书面调查项目。
我们在 22 至 23 岁时对 230 名 VLBW 年轻成年人(幸存者的 71%)和 69 名对照组进行了访谈。VLBW 年轻成年人比对照组轻 5.6 公斤,矮 4.2 厘米,接受高等教育/培训的比例较低(差异百分比[95%置信区间]:-13.1[-21.6 至-1.8]),大学学位完成率较低(-15.6[-28.0 至-4.8]),更多地依赖福利(23.5[10.2 至 35.0]),很少或没有朋友(20.5[7.2 至 32.2]),过去一年中更常出现喘息(20.1[9.0 至 28.6])。然而,在许多领域,VLBW 队列与对照组之间没有差异,VLBW 成年人对其整体生活质量和行为功能的评价与同龄人相似。以前有残疾的人在社会、职业和身体功能方面比其他 VLBW 年轻成年人差。
尽管有一些健康、教育和社会困难的证据,但以前的 VLBW 年轻成年人在健康和社会功能的许多方面与同龄人的评分相似,有些差异主要限于以前有残疾的人。