*Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia; and †Centre for Eye Research Australia, University of Melbourne, East Melbourne, Victoria, Australia.
Cornea. 2014 Jan;33(1):6-9. doi: 10.1097/ICO.0b013e3182a9fbfd.
The aim of this study is to compare long-term visual and surgical outcomes after performing deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) for keratoconus.
This is a retrospective review of 73 consecutive patients with keratoconus, managed with DALK or PK, between 2000 and 2010, by a single surgeon. Data were collected on baseline parameters, best-corrected visual acuity (BCVA) in logarithm of the mean angle of resolution (logMAR), subjective refraction, graft survival, and complications.
Thirty-one (42.5%) eyes underwent a DALK, and 42 (57.5%) eyes underwent a PK. All PK-operated and 29 out of 31 (93.5%) DALK-operated eyes remained clear at the last review. Postoperative complications were significantly more frequent after PK (57.1%) than after DALK (26.5%; P = 0.0197). The mean BCVA was not significantly different for DALK (0.14 logMAR, SD 0.2) versus PK (0.05 logMAR, SD 0.11); however, eyes that underwent PK were more likely to achieve a BCVA of 0.0 logMAR (P = 0.0029). Subjective refraction and method of visual correction (spectacles or contact lenses) were similar for each group.
DALK-operated patients in this study showed similar graft survival, fewer postoperative complications, and equivalent refractive outcomes. No significant difference in the mean BCVA was noted between DALK and PK cases.
本研究旨在比较行深板层角膜移植术(DALK)和穿透性角膜移植术(PK)治疗圆锥角膜的长期视力和手术结果。
这是一项回顾性研究,纳入了 2000 年至 2010 年间由同一位外科医生治疗的 73 例连续圆锥角膜患者,分别行 DALK 或 PK。收集的资料包括基线参数、最佳矫正视力(BCVA)对数最小分辨角对数(logMAR)、主观屈光、移植物存活率和并发症。
31 只(42.5%)眼行 DALK,42 只(57.5%)眼行 PK。所有 PK 手术眼和 31 只 DALK 手术眼中的 29 只(93.5%)在最后一次随访时仍保持透明。PK 术后并发症发生率(57.1%)明显高于 DALK 术后(26.5%;P = 0.0197)。DALK 组(0.14 logMAR,标准差 0.2)和 PK 组(0.05 logMAR,标准差 0.11)的平均 BCVA 无显著差异;然而,PK 组更有可能达到 BCVA 0.0 logMAR(P = 0.0029)。两组的主观屈光和视力矫正方法(眼镜或隐形眼镜)相似。
本研究中 DALK 组患者移植物存活率相似,术后并发症更少,屈光结果相当。DALK 组和 PK 组之间的平均 BCVA 无显著差异。