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颞骨内创伤性面神经神经瘤:多种病因的证据。

Intratemporal traumatic neuromas of the facial nerve: evidence for multiple etiologies.

机构信息

*Department of Otolaryngology-Head and Neck Surgery, and †Department of Pathology, University of Texas Southwestern Medical Center, Dallas, Texas, U.S.A.

出版信息

Otol Neurotol. 2014 Feb;35(2):e69-72. doi: 10.1097/MAO.0000000000000136.

Abstract

OBJECTIVE

To describe 2 patients with traumatic neuromas of the intratemporal facial nerve in the absence of trauma.

STUDY DESIGN

Retrospective case review.

SETTING

Tertiary care referral center.

PATIENTS

Patients included underwent resection of an intratemporal facial nerve mass. Upon pathologic evaluation, the patients were found to have traumatic neuromas of the facial nerve.

INTERVENTION(S): Patients underwent resection of an intratemporal facial traumatic neuroma. Histopathologic evaluation was performed including an immunohistochemistry evaluation.

RESULTS

Two patients were identified with intratemporal facial nerve traumatic neuromas. The patients had no significant history of trauma or chronic inflammatory process. Pathologic evaluations, including immunohistochemistry, of the excised masses were consistent with traumatic neuromas. All tumors were noted to have a disorganized collection of axons and were not consistent with the expected diagnosis of schwannoma. Tumors involved the tympanic and vertical segments of the facial nerve. A cavernous angioma was found within one mass and is thought to be the etiology of neuroma formation.

CONCLUSION

Traumatic neuromas are possible in the intratemporal facial nerve in the absence of trauma. A cavernous angioma of the facial nerve is a newly described possible cause of traumatic neuroma formation.

摘要

目的

描述 2 例无创伤史的颞骨内面神经创伤性神经瘤病例。

研究设计

回顾性病例研究。

设置

三级转诊中心。

患者

患者均接受了颞骨面神经肿块切除术。病理评估发现患者面神经有创伤性神经瘤。

干预措施

患者接受了颞骨面神经创伤性神经瘤切除术。进行了组织病理学评估,包括免疫组织化学评估。

结果

发现 2 例颞骨内面神经创伤性神经瘤患者。患者无明显创伤或慢性炎症病史。切除肿块的病理评估,包括免疫组织化学,与创伤性神经瘤一致。所有肿瘤均可见轴突排列紊乱,不符合施万细胞瘤的预期诊断。肿瘤累及面神经鼓室段和垂直段。一个肿块内发现海绵状血管畸形,被认为是神经瘤形成的病因。

结论

在无创伤的情况下,颞骨内面神经可能发生创伤性神经瘤。面神经海绵状血管畸形是创伤性神经瘤形成的一个新的可能原因。

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