约旦一组孕妇中牙周疾病与不良妊娠结局之间的关联。
Association between periodontal disease and adverse pregnancy outcomes in a cohort of pregnant women in Jordan.
作者信息
Alchalabi H A, Al Habashneh R, Jabali O Al, Khader Y S
机构信息
Department of Obstetrics and Gynecology, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan.
出版信息
Clin Exp Obstet Gynecol. 2013;40(3):399-402.
BACKGROUND
The relationship between periodontal disease (PD) and adverse pregnancy outcomes remain unclear. The authors' objective was to assess the risk of adverse pregnancy outcomes in Jordanian women with periodontal disease compared to those without.
MATERIALS AND METHODS
Between April 2009 and June 2010, 277 pregnant women with no systemic diseases at gestational age < 20 weeks were enrolled in the study. Dental and oral health examination was performed at enrollment after demographic, medical, and obstetrical information were recorded. Pregnancy outcomes were obtained by phone contact and review of medical records.
RESULTS
The incidence of periodontal disease in the pregnant women enrolled was 31%. Women with PD were at higher risk for developing preeclampsia (PE), preterm birth (PB), and low birth weight (LBW). The rate of PE in women with PD was 18.6% compared to 7.3% in the control group (p = 0.005) (OR = 2.7, 95% CI: 1.2, 6.0). The OR for PB was (4.4, 95% CI: 1.7, 11.7) and for LBW was (3.5, 95% CI: 1.6, 7.5).
CONCLUSIONS
PD is associated with increased risk of PE, PB, and LBW in healthy Jordanian women.
背景
牙周疾病（PD）与不良妊娠结局之间的关系仍不明确。作者的目的是评估患有牙周疾病的约旦女性与未患牙周疾病的女性相比出现不良妊娠结局的风险。
材料与方法
在2009年4月至2010年6月期间，277名孕龄小于20周且无全身性疾病的孕妇被纳入研究。在记录人口统计学、医学和产科信息后，于入组时进行牙齿和口腔健康检查。通过电话联系和查阅病历获取妊娠结局。
结果
纳入的孕妇中牙周疾病的发生率为31%。患有牙周疾病的女性患先兆子痫（PE）、早产（PB）和低出生体重（LBW）的风险更高。患有牙周疾病的女性中PE的发生率为18.6%，而对照组为7.3%（p = 0.005）（OR = 2.7，95% CI：1.2，6.0）。PB的OR为（4.4，95% CI：1.7，11.7），LBW的OR为（3.5，95% CI：1.6，7.5）。
结论
在健康的约旦女性中，牙周疾病与先兆子痫（PE）、早产（PB）和低出生体重（LBW）风险增加相关。
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