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经皮电刺激神经对组织修复的影响:文献综述。

The effects of transcutaneous electrical nerve stimulation on tissue repair: A literature review.

作者信息

Machado Aline Fernanda Perez, Santana Eduardo Ferreira, Tacani Pascale Mutti, Liebano Richard Eloin

机构信息

Physical Therapy Department, São Paulo City University, São Paulo, Brazil.

出版信息

Can J Plast Surg. 2012 Winter;20(4):237-40.

Abstract

BACKGROUND

Transcutaneous electrical nerve stimulation (TENS) consists of a generic application of low-frequency, pulsed electrical currents transmitted by electrodes through the skin surface. It is a therapeutic modality that is nonpharmacological, noninvasive, inexpensive, easy to use and widely applied in clinical practice.

OBJECTIVE

To narratively review the scientific evidence of the effects of TENS on tissue repair with respect to wound healing, skin flap viability and tendinous repair.

METHODS

The study was conducted using the MEDLINE, Lilacs and Scielo databases, without limit to the period of publication, and was completed in November 2011. Inclusion criteria were randomized or nonrandomized, controlled or noncontrolled clinical trials, and experimental trials involving rats subjected to TENS for tissue repair.

RESULTS

Thirty articles on tissue repair were found and, among these, 14 reported on wound healing, 14 reported on skin flaps and two analyzed tedinous repair.

DISCUSSION

It was suggested that TENS stimulates skin wound healing and tendon repair, as well as the viability of random skin flaps. Such effects may be due to the release of substance P and calcitonin gene-related peptide, which would increase blood flow and, consequently, hasten the events leading to tissue repair.

CONCLUSIONS

Based on the scientific evidence regarding the effects of TENS on tissue repair, the findings of the present literature review were inconclusive because data from the randomized controlled clinical trials were insufficient to confirm such effects.

摘要

背景

经皮电刺激神经疗法(TENS)是一种通过电极经皮肤表面传输低频脉冲电流的通用疗法。它是一种非药物、非侵入性、廉价、易于使用且在临床实践中广泛应用的治疗方式。

目的

对TENS在伤口愈合、皮瓣存活和肌腱修复方面对组织修复作用的科学证据进行叙述性综述。

方法

本研究使用MEDLINE、Lilacs和Scielo数据库进行,不限发表时间,于2011年11月完成。纳入标准为随机或非随机、对照或非对照临床试验,以及涉及接受TENS进行组织修复的大鼠的实验性试验。

结果

共找到30篇关于组织修复的文章,其中14篇报道了伤口愈合情况,14篇报道了皮瓣情况,2篇分析了肌腱修复情况。

讨论

有人提出,TENS可刺激皮肤伤口愈合和肌腱修复,以及随意皮瓣的存活。这种作用可能是由于P物质和降钙素基因相关肽的释放,这会增加血流量,从而加速导致组织修复的过程。

结论

基于关于TENS对组织修复作用的科学证据,本综述的结果尚无定论,因为随机对照临床试验的数据不足以证实这些作用。

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本文引用的文献

1
An investigation of the development of analgesic tolerance to TENS in humans.
Pain. 2011 Feb;152(2):335-342. doi: 10.1016/j.pain.2010.10.040. Epub 2010 Dec 8.
3
The effect of transcutaneous electrical nerve stimulation on postmastectomy skin flap necrosis.
Breast Cancer Res Treat. 2009 Oct;117(3):611-4. doi: 10.1007/s10549-009-0335-z. Epub 2009 Feb 15.
4
Effectiveness of transcutaneous electrical nerve stimulation for treatment of hyperalgesia and pain.
Curr Rheumatol Rep. 2008 Dec;10(6):492-9. doi: 10.1007/s11926-008-0080-z.
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Effect of electrical stimulation waveform on healing of ulcers in human beings with spinal cord injury.
Wound Repair Regen. 1996 Jan-Mar;4(1):21-8. doi: 10.1046/j.1524-475X.1996.40106.x.
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Transcutaneous electrical nerve stimulation in viability of a random skin flap in nicotine-treated rats.
Ann Plast Surg. 2006 Dec;57(6):670-2. doi: 10.1097/01.sap.0000235503.74038.a9.
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Effect of high frequency transcutaneous electrical nerve stimulation on viability of random skin flap in rats.
Acta Cir Bras. 2006 May-Jun;21(3):133-8. doi: 10.1590/s0102-86502006000300003. Epub 2006 May 26.

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