Battaglia S, Albini Riccioli L, Bartiromo F, Galassi E, Marliani A F, Leonardi M
Neuroradiology Department, Bellaria Hospital; Bologna, Italy -
Neuroradiol J. 2007 Oct 31;20(5):500-3. doi: 10.1177/197140090702000504.
Primary spinal cord tumors in children are uncommon and account for approximately 5% of all pediatric central nervous system tumors. Intracranial metastases from primary spinal cord tumors have rarely been reported. Spinal cord glioblastoma in children mainly involves the thoracic region, whereas involvement of the medullaris conus with intracranial dissemination has been described in six cases. This paper describes a pediatric case of thoracic glioblastoma multiforme with intracranial dissemination in the early stage of the clinical course and discuss the clinical and neuroradiological manifestations, the possible patterns of dissemination and finally to consider the therapeutic implications.
儿童原发性脊髓肿瘤并不常见,约占所有儿童中枢神经系统肿瘤的5%。原发性脊髓肿瘤的颅内转移很少有报道。儿童脊髓胶质母细胞瘤主要累及胸段,而终丝受累并伴有颅内播散的情况已有6例报道。本文描述了1例临床病程早期出现颅内播散的儿童胸段多形性胶质母细胞瘤病例,并讨论了其临床和神经放射学表现、可能的播散模式,最后探讨了治疗意义。