Zippi Maddalena, Pica Roberta, Scialpi Renzo, Cassieri Claudio, Avallone Eleonora Veronica, Occhigrossi Giuseppe
Maddalena Zippi, Roberta Pica, Claudio Cassieri, Eleonora Veronica Avallone, Giuseppe Occhigrossi, Department of Gastroenterology and Digestive Endoscopy, Sandro Pertini Hospital, 00157 Rome, Italy.
World J Clin Cases. 2013 Apr 16;1(1):49-51. doi: 10.12998/wjcc.v1.i1.49.
Schwannoma is a tumor originating from the Schwann cells. Gastrointestinal schwannomas are uncommon stromal tumors of the intestinal tract and, in particular, rectal schwannomas are extremely rare. In fact, it is well established that schwannomas appear more frequently in the stomach and in the small intestine, while location in the colon or in the rectum is uncommon. Reading the literature, only few cases of rectal schwannoma have been reported. Their diagnosis is confirmed by the immunohistochemical panel (S-100 protein). When these tumors are located in the colon and in the rectum, radical excision with wide margins is mandatory, due to their tendency to recur locally or become malignant, if left untreated. In the present study, we describe a case of a rectal schwannoma occured in a 72-year-old man, presented as a small polypoid lesion, which was successfully removed in toto by hot-biopsy, during the same endoscopy, due to the dimensons. No recurrence of the lesion was observed after 6 mo of follow-up.
施万细胞瘤是一种起源于施万细胞的肿瘤。胃肠道施万细胞瘤是肠道罕见的间质瘤,尤其是直肠施万细胞瘤极为罕见。事实上,众所周知,施万细胞瘤在胃和小肠中更常见,而在结肠或直肠中则不常见。查阅文献,仅报道了少数直肠施万细胞瘤病例。其诊断通过免疫组织化学检测(S-100蛋白)得以证实。当这些肿瘤位于结肠和直肠时,由于其有局部复发或恶变的倾向,若不治疗,必须进行广泛切缘的根治性切除。在本研究中,我们描述了一例发生在一名72岁男性身上的直肠施万细胞瘤病例,表现为一个小的息肉样病变,由于其大小,在同一次内镜检查中通过热活检成功完整切除。随访6个月后未观察到病变复发。