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成人移位型锁骨中段骨折的手术治疗与非手术治疗:一项系统评价

Operative versus nonoperative treatment of displaced midshaft clavicle fractures in adults: a systematic review.

作者信息

Rehn Carl-Henrik, Kirkegaard Martin, Viberg Bjarke, Larsen Morten Schultz

机构信息

Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Sdr. Boulevard 29, 5000, Odense C, Denmark,

出版信息

Eur J Orthop Surg Traumatol. 2014 Oct;24(7):1047-53. doi: 10.1007/s00590-013-1370-3. Epub 2013 Dec 10.

Abstract

OBJECTIVES

Intervention studies of clavicle fracture treatment are numerous, but only a few high quality studies prospectively compare operative and nonoperative treatment. The objective of this study was to review evidence from randomized controlled trials on operative versus nonoperative treatment of displaced midshaft clavicle fractures in adults with focus on fracture healing, complications and functional outcome.

DATA SOURCES

An electronic search was performed of PubMed, Embase and Cochrane databases which revealed 559 articles. All articles published before October 18th 2012 and written in English, Danish or Swedish were eligible.

STUDY SELECTION

Articles were excluded if they included children under the age of 16, did not include acute midshaft fractures, included concomitant fractures, did not meet the requirements of Level I evidence according to Centre for evidence based medicine 2009 guidelines, were systematic reviews or meta-analyses, or did not compare operative and nonoperative treatment.

DATA EXTRACTION

Articles were parsed for relevance by two reviewers independently regarding title, abstract, and full text. Extraction of data was done by both reviewers in collaboration and sorted according to the aims of the study. Complications were grouped according to additional surgery required. The quality of studies was assessed by both reviewers in unison using Critical Appraisal Skills Programme 2010 checklists.

CONCLUSIONS

It seems like operative intervention leads to fewer nonunions at the cost of an increase in minor complications compared to nonoperative treatment. However, the effects of operation on functional outcome remains controversial. High quality evidence is currently sparse supporting either operative or nonoperative treatment on displaced midshaft clavicle fractures in adults.

摘要

目的

关于锁骨骨折治疗的干预性研究众多,但只有少数高质量研究对手术治疗和非手术治疗进行前瞻性比较。本研究的目的是回顾随机对照试验的证据,以探讨成人移位性中段锁骨骨折的手术与非手术治疗,重点关注骨折愈合、并发症及功能结局。

数据来源

对PubMed、Embase和Cochrane数据库进行电子检索,共检索到559篇文章。所有在2012年10月18日前发表且语言为英语、丹麦语或瑞典语的文章均符合要求。

研究选择

若文章纳入16岁以下儿童、未纳入急性中段骨折、包含合并骨折、不符合2009年循证医学中心指南中I级证据的要求、为系统评价或Meta分析,或未比较手术与非手术治疗,则予以排除。

数据提取

两名审阅者独立根据文章标题、摘要和全文判断其相关性。数据提取由两名审阅者合作完成,并根据研究目的进行分类。并发症根据所需的额外手术进行分组。研究质量由两名审阅者共同使用2010年批判性评估技能计划清单进行评估。

结论

与非手术治疗相比,手术干预似乎能减少骨不连的发生,但代价是轻微并发症有所增加。然而,手术对功能结局的影响仍存在争议。目前,关于成人移位性中段锁骨骨折手术或非手术治疗的高质量证据较为匮乏。

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