眼眶免疫球蛋白G4相关性疾病：病例系列及文献综述
Orbital immunoglobulin-G4-related disease: case series and literature review.
作者信息
Mulay Kaustubh, Aggarwal Ekta, Jariwala Mehul, Honavar Santosh G
机构信息
National Reporting Centre for Ophthalmic Pathology (NRCOP), Centre for Sight, Hyderabad, India; Ophthalmic Pathology Service, L.V. Prasad Eye Institute, Hyderabad, India.
出版信息
Clin Exp Ophthalmol. 2014 Sep-Oct;42(7):682-7. doi: 10.1111/ceo.12284. Epub 2014 Jan 13.
Immunoglobulin-G4-related disease (IgG4-RD) is a distinct group of diseases characterized by elevated serum IgG4 titres and infiltration of affected organs by IgG4-positive plasma cells. IgG4-RD can involve any ocular adnexal tissue. They have a distinct prognosis and pattern of tissue involvement and hence need to be differentiated from orbital lesions with similar clinicopathological features. We report three cases of IgG4-RD and review the literature extensively discussing various aspects of this novel entity.
免疫球蛋白 G4 相关疾病（IgG4-RD）是一组独特的疾病，其特征为血清 IgG4 滴度升高以及 IgG4 阳性浆细胞浸润受累器官。IgG4-RD 可累及任何眼附属器组织。它们具有独特的预后和组织受累模式，因此需要与具有相似临床病理特征的眼眶病变相鉴别。我们报告 3 例 IgG4-RD 病例，并广泛回顾文献，讨论这一新型疾病实体的各个方面。
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