Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada.
San Raffaele Scientific Institute and EMO-GVM Centro Cuore Columbus, Milan, Italy.
JACC Cardiovasc Interv. 2014 Jan;7(1):81-8. doi: 10.1016/j.jcin.2013.07.013. Epub 2013 Dec 11.
This study sought to evaluate the feasibility of performing contemporary bifurcation techniques with the Absorb everolimus-eluting bioresorbable vascular scaffold (Abbott Vascular, Santa Clara, California) (BVS).
The feasibility of using the BVS in bifurcation lesions is unknown.
We performed bifurcation stenting procedures including main-vessel stenting with ballooning of the side branch through the BVS struts, T-stenting and crush and culotte procedures, in a synthetic arterial model. Low-pressure final kissing balloon (FKB) inflation was performed to complete the procedures.
Single-stent procedures optimally opened the side-branch ostium without deforming the main vessel BVS. T-stenting completely covered the side-branch ostium. In crush cases, we could easily re-cross the crushed BVS with the wire and balloon and achieve good results after deployment of the main-vessel BVS and FKB inflation. A 2-BVS culotte resulted in good paving of the main vessel. Disruption of 1 BVS strut was observed after FKB inflation with the 2 balloons inflated beyond the recommended limit of the BVS, as calculated by Finet's law.
Intervention of bifurcation lesions using the Absorb BVS using modern bifurcation techniques appears feasible in a coronary bifurcation model. Provisional stenting is recommended in the majority, with sequential balloon inflations and FKB inflation only when necessary. T or T-stenting and small protrusion stenting with a metal drug-eluting stent is preferable in case of crossover. A2-BVS, T-stent technique can be performed in a high-angle bifurcation; otherwise, crush or culotte should be considered, using metal DES in the side branch. Two-BVS crush and culotte require careful evaluation, and should only be considered in patients with large-caliber main vessels.
本研究旨在评估使用雅培血管公司(加利福尼亚州圣克拉拉)的 Absorb 依维莫司洗脱生物可吸收血管支架(BVS)进行当代分叉技术的可行性。
BVS 在分叉病变中的使用可行性尚不清楚。
我们在合成动脉模型中进行了分叉支架置入术,包括通过 BVS 支柱对侧支进行主血管支架置入术、T 支架置入术和 crush 及 culotte 术,同时进行低压最终吻球囊(FKB)扩张以完成手术。
单支架术最优地开放了侧支开口,而不会使主血管 BVS 变形。T 支架完全覆盖了侧支开口。在 crush 病例中,我们可以轻松地用导丝和球囊重新穿过被 crush 的 BVS,并在主血管 BVS 和 FKB 扩张后获得良好的结果。2 个 BVS 的 culotte 导致主血管良好的铺放。当 2 个球囊膨胀超过 Finet 定律计算的 BVS 推荐极限时,观察到 FKB 膨胀后 1 个 BVS 支柱的断裂。
在冠状动脉分叉模型中,使用 Absorb BVS 使用现代分叉技术介入分叉病变似乎是可行的。大多数情况下建议采用临时支架置入术,仅在必要时进行序贯球囊扩张和 FKB 扩张。在需要交叉时,推荐采用 T 支架或 T 支架技术和小突出支架置入术的金属药物洗脱支架。在高角度分叉中可以进行 A2-BVS、T 支架技术;否则,应考虑 crush 或 culotte,并在侧支中使用金属 DES。双 BVS crush 和 culotte 需要仔细评估,并且仅应在主血管口径较大的患者中考虑。