Donat H, Schiller S
Zentralbl Gynakol. 1986;108(19):1153-63.
The aetiology of carcinomas is not yet clear and the existence of tumour-specific antigens is not undoubtedly demonstrated but it is certain that the tumours are in near correlation with immunological mechanisms. It is established that certain immunophenomena exist in patients with malignomas. The tumour-associated antigens have a practical importance as tumour markers especially for the course of the disease and the recognizing of recidivation of certain carcinomas. The successes of immunotherapy of malignant tumours are not satisfactory. Better results will be expected by the use of monoclonal antibodies.
癌的病因尚不清楚,肿瘤特异性抗原的存在也未得到确凿证实,但肿瘤与免疫机制密切相关这一点是肯定的。已证实恶性肿瘤患者存在某些免疫现象。肿瘤相关抗原有重要的实际意义,可作为肿瘤标志物,尤其是对于疾病进程以及某些癌症复发的识别。恶性肿瘤免疫治疗的效果并不理想。使用单克隆抗体有望取得更好的结果。