Institute of Biochemistry, Westfälische Wilhelms Universität, Wilhelm-Klemm-Str.2, Münster, 48149, Germany; Institute of Medical Physics and Biophysics, Westfälische Wilhelms Universität, Robert-Koch-Str. 31, Münster, 48149, Germany.
Small. 2014 Mar 26;10(6):1069-75. doi: 10.1002/smll.201300315. Epub 2013 Dec 12.
Interaction between hydrophobic nanoparticles (NPs) and a pulmonary surfactant (PS) film leads to a shift in molecular packing of surfactant molecules in the PS film around the interacting NPs. The resultant structural arrangement of surfactants around the NPs may be a potential structural factor responsible for their high retention ability within the film. Moreover, during this interaction, surfactant molecules coat the NPs and change their surface properties.
疏水性纳米粒子（NPs）与肺表面活性剂（PS）膜之间的相互作用导致 PS 膜中围绕相互作用的 NPs 的表面活性剂分子的分子堆积发生位移。 NPs 周围表面活性剂的这种结构排列可能是其在膜内高保留能力的潜在结构因素。此外，在这种相互作用过程中，表面活性剂分子包裹 NPs 并改变其表面性质。
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