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大卫手术:单中心10年经验。

David operation: single center 10-year experience.

作者信息

Malvindi P G, Cappai A, Basciu A, Raffa G M, Barbone A, Citterio E, Ornaghi D, Tarelli G, Settepani F

机构信息

Department of Cardiac Surgery, Humanitas Clinical and Research Center, Rozzano, Milan, Italy -

出版信息

J Cardiovasc Surg (Torino). 2015 Aug;56(4):639-45. Epub 2013 Dec 17.

Abstract

AIM

Aortic valve-sparing operation has been progressively widely performed for the treatment of aortic root aneurysm. Nowadays, this procedure has been proposed even in presence of a bicuspid aortic valve, severe aortic regurgitation or in primary aortic dissection repair. We present our ten-year experience focusing on mid-term echocardiographic follow-up.

METHODS

Between June 2002 and February 2012, 139 patients (mean age of 61±12 years) underwent aortic valve-sparing operation with valve reimplantation. Twenty-seven patients (19%) had bicuspid aortic valve; in eighteen cases (13%) cusp motion or anatomical abnormalities concurred in determining aortic regurgitation and needed an adjunct cusp repair. A Gelweave Valsalva™ graft was implanted in all the patients.

RESULTS

The mortality pre-discharge was 0.7% (1 patient). The cumulative 1-year, 5-years and 8-years survival rates were 99%, 93% and 87% respectively. Postoperative aortic regurgitation more than mild degree (>2+/4+) was the only significant risk factors for redo aortic valve surgery Freedom from reoperation due to aortic valve regurgitation was 96% at 1 year, 90% at 5 years and 86% at 8 years. When comparing freedom from reoperation in patients with bicuspid vs tricuspid aortic valve, no differences were found (P=0.31) and the rate of aortic valve reoperation was significantly higher (P<0.001) in patients who received leaflet's repair.

CONCLUSION

The durability of valve reimplantation was found to be excellent in patients with tricuspid aortic valve and normal or nearly normal cusps. Cusp prolapse and complication after cusp repair turned out to be the main causes for early failure.

摘要

目的

保留主动脉瓣手术已逐渐广泛应用于主动脉根部瘤的治疗。如今,即使存在二叶式主动脉瓣、严重主动脉瓣反流或在原发性主动脉夹层修复中也已提出采用该手术方法。我们介绍我们十年的经验,重点是中期超声心动图随访。

方法

2002年6月至2012年2月期间,139例患者(平均年龄61±12岁)接受了保留主动脉瓣的瓣膜再植入手术。27例患者(19%)有二叶式主动脉瓣;18例(13%)瓣叶运动或解剖异常共同导致主动脉瓣反流,需要进行辅助瓣叶修复。所有患者均植入了Gelweave Valsalva™人工血管。

结果

出院前死亡率为0.7%(1例患者)。1年、5年和8年的累积生存率分别为99%、93%和87%。术后主动脉瓣反流超过轻度程度(>2+/4+)是再次进行主动脉瓣手术的唯一重要危险因素。因主动脉瓣反流再次手术的免再手术率1年时为96%,5年时为90%,8年时为86%。比较二叶式主动脉瓣与三叶式主动脉瓣患者的免再手术率,未发现差异(P=0.31),接受瓣叶修复的患者主动脉瓣再次手术率显著更高(P<0.001)。

结论

发现三叶式主动脉瓣且瓣叶正常或接近正常的患者瓣膜再植入的耐久性极佳。瓣叶脱垂和瓣叶修复后的并发症是早期失败的主要原因。

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