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定义肾脏生物学以了解肾脏疾病。

Defining kidney biology to understand renal disease.

作者信息

Little Melissa H, Brown Dennis, Humphreys Benjamin D, McMahon Andrew P, Miner Jeffrey H, Sands Jeff M, Weisz Ora A, Mullins Chris, Hoshizaki Deborah

机构信息

Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia;, †Center for Systems Biology and Program in Membrane Biology, and Division of Nephrology, Massachussetts General Hospital, Harvard University, Boston, Massachusetts;, ‡Renal Division, Brigham and Women's Hospital, Harvard University, Boston, Massachusetts;, §Stem Cell Biology and Regenerative Medicine, University of Southern California, Los Angeles, California;, ‖Renal Division, Washington University School of Medicine, Washington University in St. Louis, St. Louis, Missouri;, ¶Departments of Medicine and Physiology, Emory University School of Medicine, Atlanta, Georgia;, *Renal-Electrolyte Division, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, ††National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

出版信息

Clin J Am Soc Nephrol. 2014 Apr;9(4):809-11. doi: 10.2215/CJN.10851013. Epub 2013 Dec 26.

Abstract

The Kidney Research National Dialogue represents a novel effort by the National Institute of Diabetes and Digestive and Kidney Diseases to solicit and prioritize research objectives from the renal research and clinical communities. The present commentary highlights selected scientific opportunities specific to the study of renal development, physiology, and cell biology. Describing such fundamental kidney biology serves as a necessary foundation for translational and clinical studies that will advance disease care and prevention. It is intended that these objectives foster and focus scientific efforts in these areas in the coming decade and beyond.

摘要

肾脏研究全国对话是美国国立糖尿病、消化和肾脏疾病研究所的一项新举措,旨在从肾脏研究和临床领域征集研究目标并确定其优先顺序。本评论重点介绍了肾脏发育、生理学和细胞生物学研究特有的一些科学机遇。描述此类基础肾脏生物学是推进疾病治疗和预防的转化研究及临床研究的必要基础。旨在这些目标在未来十年及以后促进并聚焦这些领域的科研工作。

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