Division of Respiratory Medicine, Niigata University Graduate School of Medical and Dental Sciences , Niigata , Japan.
Mod Rheumatol. 2003 Jun;13(2):181-4. doi: 10.3109/s10165-002-0220-7.
Abstract We report the case of a 52-year-old man with Wegener's granulomatosis complicated with seropneumothorax. Pneumothorax or seropneumothorax has previously been reported as a rare complication of Wegener's granulomatosis. The patient was successfully treated with prednisolone and cyclophosphamide, and seropneumothorax was resolved without tube drainage. This case suggests that the pathogenesis of seropneumothorax may be associated with the disease activity of Wegener's granulomatosis because it developed spontaneously before treatment with immunosuppressive agents and without being complicated by infection.
摘要 我们报告了一例 52 岁男性 Wegener 肉芽肿合并血清性气胸病例。气胸或血清性气胸以前曾被报道为 Wegener 肉芽肿的罕见并发症。患者经泼尼松龙和环磷酰胺治疗后成功治愈,且血清性气胸无需引流管而自行消退。该病例提示血清性气胸的发病机制可能与 Wegener 肉芽肿的疾病活动有关,因为在使用免疫抑制剂治疗之前,它是自发发生的,并且没有合并感染。