Department of Urology, Columbia University Medical Center , New York, New York.
J Endourol. 2014 May;28(5):544-8. doi: 10.1089/end.2013.0783. Epub 2014 Jan 30.
While robot-assisted radical prostatectomy (RARP) is associated with shortened convalescence and decreased blood loss over open prostatectomy, little objective data is available regarding postoperative pain/discomfort and use of analgesic medications after RARP. We sought to examine these parameters in a contemporary cohort.
From 2011 to 2013, patients undergoing RARP were prospectively enrolled in a study to examine various pain parameters and carefully monitor opiate and other analgesic medication use while the patient recovered in the hospital. After discharge, the patients were asked to fill out a daily questionnaire regarding their pain parameters and self-report opiate usage. All questionnaires were based on the Wong-Baker FACES pain rating scale (0-10). Opiate dosages were converted to the approximate oral morphine sulfate equivalent dose (MSE).
A total of 60 patients, mean age 61 years, were enrolled in the study, underwent RARP, and completed follow-up questionnaires. None had a history of chronic narcotic use. Intraoperative opiate use was 94.1 mg MSE. There were 73.3% who received immediate postoperative ketorolac. After RARP, the main source of pain/discomfort was abdominal/incisional, followed by urethral catheter-related, penile, and bladder spasm-related discomfort. Abdominal pain was generally moderate for most patients and decreased significantly after about 4 days. Penile and urethral catheter-related discomfort was mild throughout the study period. Opiate analgesic medication use quickly decreased as the subjective pain scores improved.
After RARP, most patients experience mild/moderate abdominal discomfort, which improves steadily over several days. There is also a quick decline in the average opiate pain medication use that corresponds to the subjective improvement in pain symptoms. This information is useful for clinicians counseling patients on the pain associated with RARP and can serve as a reference to compare the convalescence associated with the other options for treatment of patients with localized prostate cancer.
虽然机器人辅助根治性前列腺切除术(RARP)与开放前列腺切除术相比具有缩短恢复期和减少出血量的优势,但关于 RARP 后术后疼痛/不适和镇痛药使用的客观数据很少。我们旨在研究当代队列中的这些参数。
2011 年至 2013 年,前瞻性地招募接受 RARP 的患者参加一项研究,以检查各种疼痛参数,并在患者住院康复期间仔细监测阿片类药物和其他镇痛药的使用。出院后,患者被要求填写一份关于他们的疼痛参数和自我报告阿片类药物使用情况的每日问卷。所有问卷均基于 Wong-Baker FACES 疼痛评分量表(0-10)。阿片类药物剂量转换为近似的口服硫酸吗啡等效剂量(MSE)。
共有 60 名平均年龄为 61 岁的患者入组研究,接受 RARP 并完成了随访问卷。他们均无慢性阿片类药物使用史。术中阿片类药物使用量为 94.1mg MSE。73.3%的患者术后立即给予酮咯酸。RARP 后,疼痛/不适的主要来源是腹部/切口,其次是尿道导管相关、阴茎和膀胱痉挛相关不适。大多数患者的腹部疼痛在大多数时候是中度的,大约 4 天后明显减轻。阴茎和尿道导管相关的不适在整个研究期间均为轻度。随着主观疼痛评分的改善,阿片类镇痛药的使用迅速减少。
RARP 后,大多数患者经历轻度/中度腹部不适,这种不适在数天内逐渐改善。阿片类止痛药的平均使用量也迅速下降,与疼痛症状的主观改善相对应。这些信息对于医生向患者提供与 RARP 相关的疼痛信息很有用,并可作为比较局部前列腺癌治疗其他选择相关恢复期的参考。