a PhD, Associate Professor, is affiliated to the School of Accounting, Economics and Finance , University of Southern Queensland , Toowoomba , Australia.
SAHARA J. 2013;10(2):89-95. doi: 10.1080/17290376.2013.870066.
To analyse the health-related quality of life (HR-QOL) in two groups of diamond miners (HIV negative and positive) in South Africa using three instruments. Two hypotheses were to be tested. One, was that the HR-QOL of HIV positive miners would be lower than that of HIV negative miners; and two, the selected instruments would behave consistently and thus all would confirm hypothesis one.
In our study, workers were recruited during a voluntary counselling and testing programme for HIV. HR-QOL were estimated using the Assessment of Quality of Life (AQOL) Mark 2, EQ-5D (EuroQOL), and Health Utilities Index 3 (HUI3) instruments. The data were analysed for utility values and for correlations between variables of interest (in particular HIV status). Goodness of fit, Pearson's r coefficient and t-tests were the statistical tests applied to the data.
Just over 1100 respondents were included in the analysis. HIV positive workers scored significantly lower on quality of life on the HUI3 as compared to HIV negative workers but this relationship did not (surprisingly) hold for the AQOL or EQ-5D. There was a significant positive correlation between all three instruments.
There was inconsistency among the instruments in measuring quality of life differences according to HIV status. The HUI3 confirmed the a priori expectation that the HR-QOL of HIV positive miners would be lower than HIV negative miners. There was no statistical difference for the AQOL and a confounding result was found for the EQ5D.
使用三种工具分析南非两组钻石矿工(HIV 阴性和阳性)的健康相关生活质量(HR-QOL)。要测试两个假设。一个是 HIV 阳性矿工的 HR-QOL 会低于 HIV 阴性矿工;另一个是,选择的工具将表现一致,因此所有工具都将证实假设一。
在我们的研究中,工人是在 HIV 自愿咨询和检测计划期间招募的。使用生活质量评估(AQOL)Mark 2、EQ-5D(欧洲五维健康量表)和健康效用指数 3(HUI3)工具来评估 HR-QOL。对效用值和感兴趣变量(特别是 HIV 状态)之间的相关性进行数据分析。适用于数据的统计测试包括拟合优度、Pearson r 系数和 t 检验。
超过 1100 名受访者被纳入分析。与 HIV 阴性工人相比,HIV 阳性工人在 HUI3 上的生活质量得分明显较低,但这种关系在 AQOL 或 EQ-5D 中并不存在(出乎意料)。这三个工具之间存在显著的正相关关系。
根据 HIV 状态,这些工具在衡量生活质量差异方面存在不一致性。HUI3 证实了 HR-QOL 的 HIV 阳性矿工将低于 HIV 阴性矿工的先验预期。AQOL 没有统计学差异,而 EQ5D 则存在混杂结果。