Abujam Bonnie, Mishra Rishabh, Aggarwal Amita
Department of Clinical Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Int J Rheum Dis. 2014 Mar;17(3):256-60. doi: 10.1111/1756-185X.12276. Epub 2014 Jan 10.
Musculoskeletal complaints are common in children. Studies from developed countries have found most to be non-inflammatory and juvenile idiopathic arthritis (JIA) to be less than 0.1%. However, there is limited data from developing countries such as India.
This cross-sectional study was conducted from March 2010 to April 2011 among school children aged 6-17 years in northern India. Prevalence of musculoskeletal complaints and JIA were determined using a questionnaire on musculoskeletal complaints. This was filled either by parents (always in children < 14 years) or children themselves. Subsequently, all children were individually met and responses verified. An abbreviated musculoskeletal examination (GALS) was performed on every child. In cases of suspected inflammatory arthritis, further investigations were performed.
Of the 2059 children (851 girls, 1208 boys) who were included in this study, mean (± SD) age was 11.5 ± 2.9 years. Joint pain (more than 1 week) was present in 158 (7.6%), back pain in 63 (3.1%) and heel pain in 62 (3%) of them. Limb pains, suggestive of 'growing pains', were present in 45 (2.1%) children. There were six suspected cases of inflammatory musculoskeletal pain; however, only one child was confirmed as having JIA (enthesitis-related arthritis). The estimated prevalence of JIA was 48/100,000 in Indian children.
Musculoskeletal complaints were not uncommon in children from a developing country like India. Estimated prevalence of JIA was 48/100,000 (95%CI 10-280).
肌肉骨骼问题在儿童中很常见。发达国家的研究发现,大多数此类问题是非炎症性的,而幼年特发性关节炎(JIA)的发病率低于0.1%。然而,来自印度等发展中国家的数据有限。
这项横断面研究于2010年3月至2011年4月在印度北部6至17岁的学童中进行。使用一份关于肌肉骨骼问题的问卷来确定肌肉骨骼问题和JIA的患病率。问卷由家长填写(14岁以下儿童始终由家长填写)或儿童自己填写。随后,与所有儿童进行单独面谈并核实回答。对每个儿童进行了简化的肌肉骨骼检查(GALS)。对于疑似炎症性关节炎的病例,进行了进一步检查。
本研究纳入的2059名儿童(851名女孩,1208名男孩)中,平均(±标准差)年龄为11.5±2.9岁。其中158名(7.6%)有持续超过1周的关节疼痛,63名(3.1%)有背痛,62名(3%)有足跟痛。45名(2.1%)儿童有提示“生长痛”的肢体疼痛。有6例疑似炎症性肌肉骨骼疼痛病例;然而,只有1名儿童被确诊为患有JIA(附着点炎相关关节炎)。印度儿童JIA的估计患病率为48/100,000。
在印度这样的发展中国家,儿童肌肉骨骼问题并不罕见。JIA的估计患病率为48/100,000(95%可信区间10 - 280)。